Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research

被引：86

作者：

Ceccarelli, Simona M. ^{[1
]}

Chomienne, Odile ^{[1
]}

Gubler, Marcel ^{[1
]}

Arduini, Arduino ^{[2
]}

机构：

[1] F Hoffmann La Roche Ltd, Div Pharmaceut, CH-4070 Basel, Switzerland

[2] CoreQuest Sagl, CH-6934 Bioggio, Switzerland

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2011年 / 54卷 / 09期

关键词：

FATTY-ACID OXIDATION; PALMOXIRATE METHYL 2-TETRADECYLGLYCIDATE; PROLIFERATOR-ACTIVATED RECEPTOR; MALONYL-COA SENSITIVITY; ORAL HYPOGLYCEMIC AGENT; PALMITOYL TRANSFERASE-I; DECREASES FOOD-INTAKE; PERFUSED RAT HEARTS; N-TERMINAL DOMAIN; HEPATIC CARNITINE;

D O I：

10.1021/jm100809g

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：3109 / 3152

页数：44

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