Epidemiological study of the systemic ophthalmological effects of carbon disulfide

A total of 123 male viscose rayon workers who were exposed to carbon disulfide, and an additional 67 workers who were not exposed to any toxic agent in the working environment, underwent a thorough ophthalmological examination. The relationship between exposure and ophthalmological results was analyzed with univariate and multivariate methods. The most striking findings were strong associations between exposure and the 100-HUE color vision score and excess of microaneurysms in the exposed group. The current threshold limit value appeared to protect against these effects.