COMPARATIVE CHEMOMAPPING OF PHYTOCONSTITUENTS FROM DIFFERENT EXTRACTS OF GLOBE ARTICHOKE - CYNARA SCOLYMUS L.

被引：0

作者：

Vigh, Szabolcs ^{[1
,2
]}

Cziaky, Zoltan ^{[2
]}

Sinka, Laszlo Tamas ^{[2
]}

Pribac, Ciprian ^{[3
]}

Mos, Liana ^{[3
]}

Turcus, Violeta ^{[3
]}

Remenyik, Judit ^{[4
]}

Mathe, Endre ^{[2
,3
,4
]}

机构：

[1] Univ Nyiregyhaza, Inst Agr Sci, Sostoi Str 31-B, H-4432 Nyiregyhaza, Hungary

[2] Univ Nyiregyhaza, Agr & Mol Res Inst, Sostoi Str 31-B, H-4432 Nyiregyhaza, Hungary

[3] Vasile Goldis Western Univ Arad, Fac Med, Liviu Rebreanu Str 91-93, RO-310414 Arad, Romania

[4] Univ Debrecen, Fac Agr & Food Sci & Environm Management, Boszormenyi Str 138, H-4032 Debrecen, Hungary

来源：

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA | 2017年 / 62卷 / 02期

关键词：

globe artichoke; Cynara scolymus; phytoconstituents; bioactive compound; LC-ESI-MS; PHENOLIC-COMPOUNDS; IN-VITRO; CAFFEOYLQUINIC ACIDS; DIETARY-SUPPLEMENTS; METHYL CINNAMATE; LEAF EXTRACT; INHIBITION; VICENIN-2; APOPTOSIS; PATHWAY;

D O I：

10.24193/subbchem.2017.2.10

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Artichoke (Cynara scolymus L.) is a well-known herb for its efficiency in the prevention/treatment of liver injuries, among other human chronic diseases. The aim of present study was to analyse the phytoconstituents content of aqueous and hydro-alcoholic extracts obtained from the leaves of artichoke. The chemomapping was carried out using UHPLC-ESI-MS. Several new and some known phytoconstituents were identified in the two type of extracts that have slightly different composition profiles. The newly found phytoconstituents in artichoke, plead for multiple health promoting effects that have presumably more stochastic than determinative features. Therefore, further experiments are needed using such extracts, and based on a system biology approach to clarify the complexity of beneficial effects of artichoke.

引用

页码：125 / 143

页数：19

共 58 条

[1] Extensive characterisation of bioactive phenolic constituents from globe artichoke (Cynara scolymus L.) by HPLC-DAD-ESI-QTOF-MS [J].

Abu-Reidah, Ibrahim M. ;

Arraez-Roman, David ;

Segura-Carretero, Antonio ;

Fernandez-Gutierrez, Alberto .

FOOD CHEMISTRY, 2013, 141 (03) :2269-2277

[2] Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity [J].

Arlt, A. ;

Sebens, S. ;

Krebs, S. ;

Geismann, C. ;

Grossmann, M. ;

Kruse, M-L ;

Schreiber, S. ;

Schaefer, H. .

ONCOGENE, 2013, 32 (40) :4825-4835

[3] Absorption and metabolism of bioactive molecules after oral consumption of cooked edible heads of Cynara scolymus L. (cultivar Violetto di Provenza) in human subjects:: a pilot study [J].

Azzini, E. ;

Bugianesi, R. ;

Romano, F. ;

Di Venere, D. ;

Miccadei, S. ;

Durazzo, A. ;

Foddai, M. S. ;

Catasta, G. ;

Linsalata, V. ;

Maiani, G. .

BRITISH JOURNAL OF NUTRITION, 2007, 97 (05) :963-969

[4] Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits [J].

Ben Salem, Maryem ;

Affes, Hanen ;

Ksouda, Kamilia ;

Dhouibi, Raouia ;

Sahnoun, Zouheir ;

Hammami, Serria ;

Zeghal, Khaled Mounir .

PLANT FOODS FOR HUMAN NUTRITION, 2015, 70 (04) :441-453

[5]

Bernhard R. A., 1972, Lebensmittel-Wissenschaft + Technologie, V5, P185

[6] Genotoxic and anti-genotoxic effects of esculin and its oligomer fractions against mitomycin C-induced DNA damages in mice [J].

Bzeouich, Imen Mokdad ;

Mustapha, Nadia ;

Maatouk, Mouna ;

Ghedira, Kamel ;

Ghoul, Mohamed ;

Chekir-Ghedira, Leila .

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2016, 82 :48-52

[7] Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2 AMPK Pathway in 3T3-L1 Preadipocytes [J].

Chen, Yun-Yu ;

Lee, Meng-Hwan ;

Hsu, Chih-Chieh ;

Wei, Chia-Li ;

Tsai, Ying-Chieh .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, 60 (04) :955-963

[8] Effect of Temperature on the Fecundity and Longevity of Ascotis selenaria (Lepidoptera: Geometridae): Developing an Oviposition Model [J].

Choi, Kyung San ;

Kim, Dong-Soon .

JOURNAL OF ECONOMIC ENTOMOLOGY, 2016, 109 (03) :1267-1272

[9] Profiling the chlorogenic acids of aster by HPLC-MSn [J].

Clifford, Michael N. ;

Zheng, Wang ;

Kuhnert, Nikolai .

PHYTOCHEMICAL ANALYSIS, 2006, 17 (06) :384-393

[10] Dose-effect study on the antioxidant properties of leaves and outer bracts of extracts obtained from Violetto di Toscana artichoke [J].

Coinu, Rita ;

Carta, Stefania ;

Urgeghe, Pier Paolo ;

MulinaCCi, Nadia ;

Pinelli, Patrizia ;

Franconi, Flavia ;

Romani, Annalisa .

FOOD CHEMISTRY, 2007, 101 (02) :524-531

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