Centering of organic-inorganic hybrid liposomal cerasomes in electrospun gelatin nanofibers

被引：7
|
作者：
Zha, Zhengbao [1 ,2 ]
Leung, Siu Ling [1 ]
Dai, Zhifei [2 ]
Wu, Xiaoyi [1 ,3 ]
机构：
[1] Univ Arizona, Dept Aerosp & Mech Engn, Tucson, AZ 85721 USA
[2] Harbin Inst Technol, Nanomed & Biosensor Lab, Sch Sci, Harbin 150080, Peoples R China
[3] Univ Arizona, Biomed Engn IDP & Inst Bio5, Tucson, AZ 85721 USA
来源：
APPLIED PHYSICS LETTERS | 2012年 / 100卷 / 03期
基金：
美国国家科学基金会;
关键词：
ELECTRICALLY FORCED JETS; MEMBRANE;
D O I：
10.1063/1.3678040
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
A study investigating the embedding of stabilized organic-inorganic liposomal cerasomes in gelatin nanofibers through the electrospinning of cerasome-dispersed gelatin aqueous solution is presented. Fluorescent and transmission electron microscopy confirm the embedding and centering of cerasomes in the electrospun nanofibers. A simple mechanism is proposed for the centering of cerasomes in gelatin nanofibers. The ability to incorporate cerasomes capable of encapsulating a variety of bioactive molecules provides a promising method to functionalize polymer nanofibers. (C) 2012 American Institute of Physics. [doi:10.1063/1.3678040]
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页数：3
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