Testing neonate-infant membrane oxygenators with the University of Texas neonatal pulsatile cardiopulmonary bypass system in vitro

被引：12

作者：

Uendar, Akif ^{[1
,2
]}

Holland, Marian C. ^{[2
,3
]}

Howelton, Russel V. ^{[1
]}

Benson, Cherie K. ^{[1
]}

Ybarra, Jose R. ^{[1
]}

Miller, O. LaWayne ^{[1
]}

Rossbach, Mario M. ^{[1
]}

Runge, Thomas M. ^{[1
,2
]}

Johnson, Scott B. ^{[1
]}

Sako, Edward Y. ^{[1
]}

Calhoon, John H. ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Cardiothorac Res Lab, Div Thorac Surg, Dept Surg, San Antonio, TX 78284 USA

[2] Univ Texas Austin, Biomed Med Engn Program, Coll Engn, Austin, TX 78712 USA

[3] Univ Texas Hlth Sci Ctr Houston, Sch Med, Houston, TX USA

来源：

PERFUSION-UK | 1998年 / 13卷 / 05期

关键词：

D O I：

10.1177/026765919801300511

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neurologic complications are already well documented after cardiopulmonary bypass (CPB) procedures in neonates and infants. Physiologic pulsatile flow CPB systems may be the alternative to the currently used steady-flow CPB circuits. In addition to the pulsatile pump, a membrane oxygenator should be chosen carefully, because only a few membrane oxygenators are suitable for physiologic pulsatile flow. We have tested four different types of neonate-infant membrane oxygenators for physiologic pulsatility with The University of Texas neonate-infant pulsatile CPB system in vitro. Evaluation criteria were based on mean ejection time, extracorporeal circuit (ECC) pressure, and upstroke of dp/dt. The results suggested that the Capiox 308 hollow-fibre membrane oxygenator produced the best physiologic pulsatile waveform according to the ejection time, ECC pressure, and the upstroke of dp/dt. The Minimax Plus and Masterflo Infant hollow-fibre membrane oxygenators also produced adequate pulsatile flow. Only the Variable Prime Cobe Membrane Lung (VPCML) Plus flat-sheet membrane oxygenator failed to reach the criteria for physiologic pulsatility. Depending on the oxygenator used, the lowest priming volume of the infant CPB circuit was 415 ml and the highest 520 ml.

引用

页码：346 / 352

页数：7

共 41 条

[1] PULSATILE REPERFUSION AFTER CARDIAC-ARREST IMPROVES NEUROLOGIC OUTCOME [J].