Serum cystatin C is associated with other cardiovascular risk markers and cardiovascular disease in elderly men

被引：14

作者：

Larsson, Anders ^{[1
]}

Helmersson, Johanna ^{[2
]}

Hansson, Lars-Olof ^{[1
]}

Basu, Samar ^{[2
]}

机构：

[1] Univ Uppsala Hosp, Dept Med Sci, Sect Clin Chem, S-75185 Uppsala, Sweden

[2] Univ Uppsala Hosp, Dept Publ Hlth & Caring Sci, Sect Clin Nutr Res, Uppsala, Sweden

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2008年 / 125卷 / 02期

关键词：

cardiovascular disease; cystatin C; diabetes mellitus; glomerular filtration rate; kidney; human;

D O I：

10.1016/j.ijcard.2007.07.113

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Renal dysfunction is associated with increased cardiovascular morbidity and mortality. The aim of this cross-sectional study was to investigate the relationship between the glomerular filtration marker cystatin C and other cardiovascular risk markers and morbidity in elderly males. Cystatin C was measured in a group of 77-year-old males (n = 792) and compared cystatin C with other known risk markers for cardiovascular disease. Cystatin C values were significantly increased in individuals with diabetes (p = 0.05) and cardiovascular diseases (p<0.0001). There were significant correlations between cystatin C values and body mass index, HbA1c, insulin, triglycerides and hsCRP. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：263 / 264

页数：2

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