Complete genomic sequence and comparative analysis of four genital and respiratory isolates of bovine herpesvirus subtype 1.2b (BoHV-1.2b), including the prototype virus strain K22

被引：16

作者：

d'Offay, Jean M. ^{[1
]}

Eberle, R. ^{[1
]}

Fulton, Robert W. ^{[1
]}

Kirkland, Peter D. ^{[2
]}

机构：

[1] Oklahoma State Univ, Ctr Vet Hlth Sci, Dept Vet Pathobiol, 118 McElroy Hall, Stillwater, OK 74078 USA

[2] Elizabeth Macarthur Agr Inst, Virol Lab, Meanagle, NSW, Australia

来源：

ARCHIVES OF VIROLOGY | 2016年 / 161卷 / 11期

关键词：

BoHV-1; BoHV-1.1; BoHV-1.2b; Bovine herpesvirus; BHV-1; Subtype; 1.2b; 1.1; Complete genome sequence; Infectious pustular vulvovaginitis; IPV; Infectious pustular balanoposthitis; IPB; Bovine respiratory disease; BRD; RHINOTRACHEITIS; INFECTION;

D O I：

10.1007/s00705-016-3026-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Bovine herpesvirus subtype 1.2b (BoHV-1.2b) is associated primarily with bovine infectious pustular vulvovaginitis. We report here the complete genomic sequence of four BoHV-1.2b isolates. The DNA sequence identity of the four genomes is 98.9 %. Differences were primarily in regions containing direct repeats, specifically gene UL36 and the terminal repeat regions immediately flanking gene BICP22. BoHV-1.2b and BoHV-1.1 genomes are similar in size (similar to 135 kb), completely orthologous with respect to regional structure and gene location, and have a 97.5 % DNA sequence homology. The most notable difference is the structure of the DNA replication origin of the two viruses.

引用

页码：3269 / 3274

页数：6