A competent pot and atom-efficient synthesis of Betti bases over nanocrystalline MgO involving a modified Mannich type reaction

被引:75
作者
Karmakar, Bikash [2 ]
Banerji, Julie [1 ]
机构
[1] Univ Calcutta, Dept Chem, Ctr Adv Studies Nat Prod Including Organ Synth, Kolkata 700009, India
[2] Gobardanga Hindu Coll, Dept Chem, Khantura 743273, India
关键词
Multicomponent synthesis; Betti base; Nanocrystalline MgO; Heterogeneous; Water chemistry; DERIVATIVES;
D O I
10.1016/j.tetlet.2011.07.075
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple, efficient, and eco-friendly method for the synthesis of 1-(alpha-aminoalkyl) naphthols, the Betti bases, has been carried out over a basic nanocrystalline MgO catalyst in aqueous condition. The method has been applied for the synthesis of a range of compounds with variable functionalities in excellent yield and selectivity. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4957 / 4960
页数:4
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