Neuromodulation intrinsic to the central pattern generator for escape swimming in Tritonia

被引:37
作者
Katz, PS [1 ]
机构
[1] Georgia State Univ, Dept Biol, Atlanta, GA 30302 USA
来源
NEURONAL MECHANISMS FOR GENERATING LOCOMOTOR ACTIVITY | 1998年 / 860卷
关键词
D O I
10.1111/j.1749-6632.1998.tb09048.x
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Extrinsic neuromodulatory inputs to central pattern generators (CPGs) can alter the properties and synaptic interactions of neurons in those circuits and thereby modify the output of the CPG. Recent work in a number of systems has now demonstrated that neurons intrinsic to CPG can also evoke neuromodulatory actions on other members of the CPG. Such "intrinsic neuromodulation" plays a role in controlling the CPG underlying the escape swim response of the nudibrach mollusc, Tritonia diomedea. The dorsal swim interneurons (DSIs) are a bilaterally represented set of three serotonergic neurons that participate in the generation of the rhythmic swim motor program. Serotonin released from these CPG neurons functions both as a fast neurotransmitter and as a slower neuromodulator. In its modulatory role, serotonin enhances the release of neurotransmitter from another CPG neuron, C2, and also increases C2 excitability by decreasing spike frequency adaptation. These neuromodulatory actions intrinsic to the CPG may be important for the initial reconfiguration of the system into a function CPG and for experience-dependent changes in the output such as behavioral sensitization and habituation.
引用
收藏
页码:181 / 188
页数:8
相关论文
共 39 条
[1]  
[Anonymous], SEROTONIN NEUROTRANS
[2]  
[Anonymous], 1989, NETWORK OSCILLATOR U
[3]  
BARNES S, 1994, J EXP BIOL, V189, P37
[4]  
Brown GD, 1996, BEHAV NEUROSCI, V110, P478
[5]   Isolated-brain parallels to simple types of learning and memory in Tritonia [J].
Brown, GD .
PHYSIOLOGY & BEHAVIOR, 1997, 62 (03) :509-518
[6]  
Byrne JH, 1996, J NEUROSCI, V16, P425
[7]   MULTIPLE NEUROPEPTIDES IN CHOLINERGIC MOTOR NEURONS OF APLYSIA - EVIDENCE FOR MODULATION INTRINSIC TO THE MOTOR CIRCUIT [J].
CROPPER, EC ;
LLOYD, PE ;
REED, W ;
TENENBAUM, R ;
KUPFERMANN, I ;
WEISS, KR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (10) :3486-3490
[8]   Regulation of rhythmic movements by purinergic neurotransmitters in frog embryos [J].
Dale, N ;
Gilday, D .
NATURE, 1996, 383 (6597) :259-263
[9]   NEURONAL BASIS OF BEHAVIOR IN TRITONIA .4. CENTRAL ORIGIN OF A FIXED ACTION PATTERN DEMONSTRATED IN ISOLATED BRAIN [J].
DORSETT, DA ;
WILLOWS, AOD ;
HOYLE, G .
JOURNAL OF NEUROBIOLOGY, 1973, 4 (03) :287-300
[10]  
Frost W. N., 1996, Society for Neuroscience Abstracts, V22, P2047