Eunicellin-based diterpenoids, australins A-D, isolated from the soft coral Cladiella australis

被引：55

作者：

Ahmed, AF

Wu, MH

Wang, GH

Wu, YC

Sheu, JH ^{[1
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Marine Resources, Kaohsiung 804, Taiwan

[2] Mansoura Univ, Fac Pharm, Dept Pharmacognosy, Mansoura 35516, Egypt

[3] Hsing Kuo Uni, Ctr Gen Educ, Tainan 709, Taiwan

[4] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung 807, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 07期

关键词：

D O I：

10.1021/np0500732

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The EtOAc extract of a Taiwanese soft coral, Caldiella australis, yielded four new eunicellin-based diterpenoids, australins A-D (1-4). The chemical structures of these metabolites were determined on the basis of extensive spectroscopic (including 1D and 2D NMR) analyses and by comparison of their NMR spectral data with those of related metabolites. Metabolite 2 was found to possess a moderate cytotoxic activity against selected breast and liver cancer cell lines.

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页码：1051 / 1055

页数：5

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