Treatment of acute hepatitis C virus infection in HIV-infected MSM: the effect of treatment duration

被引：30

作者：

Lambers, Femke A. E. ^{[1
]}

Brinkman, Kees ^{[2
]}

Schinkel, Janke ^{[3
]}

Spijkerman, Ingrid J. B. ^{[4
]}

Molenkamp, Richard ^{[3
]}

Coutinho, Roel A. ^{[5
,6
]}

Prins, Maria ^{[1
,6
]}

van der Meer, Jan T. M. ^{[6
]}

机构：

[1] Publ Hlth Serv Amsterdam, Dept Res, NL-1018 WT Amsterdam, Netherlands

[2] Onze Lieve Vrouw Hosp, Dept Internal Med, Amsterdam, Netherlands

[3] Univ Amsterdam, Acad Med Ctr, Dept Med Microbiol, Sect Clin Virol, NL-1105 AZ Amsterdam, Netherlands

[4] Onze Lieve Vrouw Hosp, Dept Med Microbiol, Amsterdam, Netherlands

[5] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands

[6] Univ Amsterdam, Acad Med Ctr, Dept Internal Med, Div Infect Dis Trop Med & AIDS CINIMA, NL-1105 AZ Amsterdam, Netherlands

来源：

AIDS | 2011年 / 25卷 / 10期

关键词：

PLUS RIBAVIRIN; HCV; RECOMMENDATIONS; POLYMORPHISM; INDIVIDUALS; TRIAL; PANEL; MEN;

D O I：

10.1097/QAD.0b013e3283480144

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated hepatitis C virus (HCV) treatment and the effect of treatment duration (24 versus 48 weeks) on treatment outcome among 50 HIV-infected men who have sex with men with acute HCV infection in Amsterdam. Overall sustained virological response (SVR) rate was 76%. Treatment duration was not significantly associated with SVR (adjusted odds ratio=2.32; 95% confidence interval 0.39-13.97), suggesting that 24-week treatment may be sufficient for acute HCV infection in HIV-coinfected patients.

引用

页码：1333 / 1336

页数：4

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