Improvement of Rheumatoid Arthritis and Autoimmune Hepatitis in a Patient Treated with the Tumor Necrosis Factor Inhibitor, Etanercept

被引：6

作者：

Umekita, Kunihiko ^{[1
]}

Miyauchi, Shunichi ^{[1
]}

Ueno, Shiro ^{[1
]}

Takajo, Ichiro ^{[1
]}

Kusumoto, Kazunori ^{[2
]}

Hasuike, Satoru ^{[2
]}

Umekita, Yoshiko ^{[3
]}

Tanaka, Hiroyuki ^{[3
]}

Nagata, Kenji ^{[2
]}

Nagatomo, Yasuhiro ^{[1
]}

Kataoka, Hiroaki ^{[3
]}

Shimoda, Kazuya ^{[2
]}

Okayama, Akihiko ^{[1
]}

机构：

[1] Miyazaki Univ, Fac Med, Dept Internal Med, Div Rheumatol Infect Dis & Lab Med, Miyazaki, Japan

[2] Miyazaki Univ, Fac Med, Dept Internal Med, Div Gastroenterol & Hematol, Miyazaki, Japan

[3] Miyazaki Univ, Fac Med, Sect Oncopathol & Regenerat Biol, Miyazaki, Japan

来源：

INTERNAL MEDICINE | 2011年 / 50卷 / 11期

关键词：

autoimmune hepatitis; rheumatoid arthritis; anti-TNF therapy; PRIMARY BILIARY-CIRRHOSIS; ANTI-TNF THERAPY; DISEASES; LIVER;

D O I：

10.2169/internalmedicine.50.4879

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of rheumatoid arthritis (RA) with autoimmune hepatitis (AIH) and Sjogren syndrome (SjS) that was treated with the tumor necrosis factor (TNF) inhibitor, etanercept (ETN). Both RA activity and transaminase levels improved as a result of treatment. Follow-up liver biopsy showed improvement of hepatitis. Although the efficacy of anti-TNF for RA patients with AIH remains controversial, this case suggests that treatment with ETN may result in a favorable clinical course in a certain subset of patients with RA and AIH.

引用

页码：1245 / 1249

页数：5

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