Saposhnikovia divaricata-An Ethnopharmacological, Phytochemical and Pharmacological Review

被引:41
作者
Yang, Min [1 ]
Wang, Cong-cong [1 ]
Wang, Wen-le [2 ]
Xu, Jian-ping [3 ]
Wang, Jie [3 ]
Zhang, Chun-hong [1 ,3 ]
Li, Min-hui [1 ,2 ,4 ,5 ]
机构
[1] Baotou Med Coll, Dept Pharm, Baotou 014060, Inner Mongolia, Peoples R China
[2] Inner Mongolia Inst Tradit Chinese Med, Pharmaceut Lab, Hohhot 010020, Peoples R China
[3] Baotou Med Coll, Inner Mongolia Key Lab Tradit Chinese Med Resourc, Baotou 014060, Inner Mongolia, Peoples R China
[4] Guangxi Bot Garden Med Plants, Guangxi Key Lab Med Resources Protect & Genet Imp, Nanning 530023, Peoples R China
[5] Baotou Med Coll, Inner Mongolia Key Lab Characterist Geoherbs Reso, Baotou 014060, Inner Mongolia, Peoples R China
关键词
Saposhnikovia divaricata; Chinese medicine; ethnopharmacology; phytochemistry; pharmacology; NF-KAPPA-B; CHEMICAL-CONSTITUENTS; O-GLUCOSYLCIMIFUGIN; INHIBITION; CHROMONES; ROOTS; IDENTIFICATION; ACTIVATION; EXTRACTION; COMPONENTS;
D O I
10.1007/s11655-020-3091-x
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Saposhnikovia divaricata (Turcz.) Schischk., a perennial herb belonging to the family Umbelliferae, is widely distributed in Northeast Asia. Its dried root (Radix Saposhnikoviae) is used as a Chinese herbal medicine for the treatment of immune system, nervous system, and respiratory diseases. Phytochemical and pharmacological studies have shown that the main constituents of S. divaricata are chromones, coumarins, acid esters, and polyacetylenes, and these compounds exhibited significant anti-inflammatory, analgesic, antioxidant, antiproliferative, antitumor, and immunoregulatory activities. The purpose of this review is to provide comprehensive information on the botanical characterization and distribution, traditional use and ethnopharmacology, phytochemistry, and pharmacology of S. divaricata for further study concerning its mechanism of action and development of better therapeutic agents and health products from S. divaricata.
引用
收藏
页码:873 / 880
页数:8
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