Sodium Glucose Cotransporter 2 (SGLT2) Inhibitors Across the Spectrum of Hypertension

被引：16

作者：

Sanidas, Elias A. ^{[1
]}

Papadopoulos, Dimitrios P. ^{[1
]}

Hatziagelaki, Erifili ^{[2
]}

Grassos, Charalampos ^{[3
]}

Velliou, Maria ^{[1
]}

Barbetseas, John ^{[1
]}

机构：

[1] Laikon Gen Hosp, Dept Cardiol, Hypertens Excellence Ctr ESH, Athens, Greece

[2] Athens Med Sch, Attikon Gen Hosp, Dept Internal Med 2, Athens, Greece

[3] KAT Gen Hosp, Hypertens Excellence Ctr ESH, Dept Cardiol, Athens, Greece

来源：

AMERICAN JOURNAL OF HYPERTENSION | 2020年 / 33卷 / 03期

关键词：

arterial hypertension; blood pressure; diabetes mellitus; SGLT-2; Inhibitors; TYPE-2; DIABETES-MELLITUS; BLOOD-PRESSURE; EMPAGLIFLOZIN; DAPAGLIFLOZIN; CANAGLIFLOZIN; REDUCTION; SAFETY; IMPACT; RHYTHM;

D O I：

10.1093/ajh/hpz157

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Sodium glucose cotransporter 2 (SGLT2) inhibitors represent a novel class of oral antihyperglycemic drugs that have been approved over the last decade for the management of type 2 diabetes mellitus. Except the glucose-lowering effects, robust evidence also suggests that SGLT2 inhibitors confer benefits in cardiovascular system. The purpose of this review was to investigate the effects of SGLT2 inhibitors across the spectrum of arterial hypertension.

引用

页码：207 / 213

页数：7

共 37 条

[1] Effects of Sodium-Glucose Cotransporter 2 Inhibitors on 24-Hour Ambulatory Blood Pressure: A Systematic Review and Meta-Analysis [J].

Baker, William L. ;

Buckley, Leo F. ;

Kelly, Michael S. ;

Bucheit, John D. ;

Parod, Eric D. ;

Brown, Roy ;

Carbone, Salvatore ;

Abbate, Antonio ;

Dixon, Dave L. .

JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2017, 6 (05)

[2] Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis [J].

Baker, William L. ;

Smyth, Lindsay R. ;

Riche, Daniel M. ;

Bourret, Emily M. ;

Chamberlin, Kevin W. ;

White, William B. .

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2014, 8 (04) :262-275

[3] SGLT2 Inhibitors and Mechanisms of Hypertension [J].

Briasoulis, Alexandros ;

Al Dhaybi, Omar ;

Bakris, George L. .

CURRENT CARDIOLOGY REPORTS, 2018, 20 (01)

[4] Effects of canagliflozin on body weight and relationship to HbA1c and blood pressure changes in patients with type 2 diabetes [J].

Cefalu, William T. ;

Stenlof, Kaj ;

Leiter, Lawrence A. ;

Wilding, John P. H. ;

Blonde, Lawrence ;

Polidori, David ;

Xie, John ;

Sullivan, Daniel ;

Usiskin, Keith ;

Canovatchel, William ;

Meininger, Gary .

DIABETOLOGIA, 2015, 58 (06) :1183-1187

[5] The effect of empagliflozin on arterial stiffness and heart rate variability in subjects with uncomplicated type 1 diabetes mellitus [J].

Cherney, David Z. I. ;

Perkins, Bruce A. ;

Soleymanlou, Nima ;

Har, Ronnie ;

Fagan, Nora ;

Johansen, Odd Erik ;

Woerle, Hans-Juergen ;

von Eynatten, Maximilian ;

Broedl, Uli C. .

CARDIOVASCULAR DIABETOLOGY, 2014, 13

[6] Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes [J].

Chilton, R. ;

Tikkanen, I. ;

Cannon, C. P. ;

Crowe, S. ;

Woerle, H. J. ;

Broedl, U. C. ;

Johansen, O. E. .

DIABETES OBESITY & METABOLISM, 2015, 17 (12) :1180-1193

[7] Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review [J].

Colosia, Ann D. ;

Palencia, Roberto ;

Khan, Shahnaz .

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2013, 6 :327-338

[8] Renal, metabolic and cardiovascular considerations of SGLT2 inhibition [J].

DeFronzo, Ralph A. ;

Norton, Luke ;

Abdul-Ghani, Muhammad .

NATURE REVIEWS NEPHROLOGY, 2017, 13 (01) :11-26

[9] Phlorizin: a review [J].

Ehrenkranz, JRL ;

Lewis, NG ;

Kahn, CR ;

Roth, J .

DIABETES-METABOLISM RESEARCH AND REVIEWS, 2005, 21 (01) :31-38

[10] Mechanisms of blood pressure reduction with sodium-glucose co-transporter 2 (SGLT2) inhibitors [J].

Filippatos, T. D. ;

Tsimihodimos, V. ;

Elisaf, M. S. .

EXPERT OPINION ON PHARMACOTHERAPY, 2016, 17 (12) :1581-1583

← 1 2 3 4 →