Recurrent Pregnancy Loss Evaluation and Treatment

被引:79
作者
Shahine, Lora [1 ,2 ,3 ]
Lathi, Ruth [4 ]
机构
[1] Pacific NW Fertil, Seattle, WA USA
[2] IVF Specialists, Seattle, WA USA
[3] Univ Washington, Sch Med, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Seattle, WA 98195 USA
[4] Stanford Univ, Sch Med, Div Reprod Endocrinol & Infertil, Stanford, CA 94305 USA
关键词
Recurrent pregnancy loss; Recurrent miscarriage; Recurrent fetal loss; Recurrent embryonic loss; PREIMPLANTATION GENETIC DIAGNOSIS; SUBSEQUENT REPRODUCTIVE-PERFORMANCE; TROPHOBLAST GONADOTROPIN-SECRETION; MATERNAL THYROID-DEFICIENCY; IN-VITRO FERTILIZATION; ANTIPHOSPHOLIPID ANTIBODIES; SPONTANEOUS-ABORTION; CHROMOSOME-ABNORMALITIES; INTRAVENOUS IMMUNOGLOBULIN; HYSTEROSCOPIC TREATMENT;
D O I
10.1016/j.ogc.2014.10.002
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Recurrent pregnancy loss (RPL) is a multifactorial condition. Approximately half of patients with RPL will have no explanation for their miscarriages. De novo chromosome abnormalities are common in sporadic and recurrent pregnancy loss. Testing for embryonic abnormalities can provide an explanation for the miscarriage in many cases and prognostic information. Regardless of the cause of RPL, patients should be reassured that the prognosis for live birth with an evidence-based approach is excellent for most patients. The authors review current evidence for the evaluation and treatment of RPL and explore the proposed use of newer technology for patients with RPL.
引用
收藏
页码:117 / +
页数:19
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