Rhodium-Catalyzed Anti-Markovnikov Intermolecular Hydroalkoxylation of Terminal Acetylenes

被引：84

作者：

Kondo, Masataka ^{[1
]}

Kochi, Takuya ^{[1
]}

Kakiuchi, Fumitoshi ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, Kanagawa 2238522, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 01期

关键词：

RAY CRYSTAL-STRUCTURE; METAL VINYLIDENES; CARBOXYLIC-ACIDS; ALKYNES; COMPLEXES; HYDRATION; ALCOHOLS; ETHERS; TRANSFORMATION; ALDEHYDES;

D O I：

10.1021/ja1097385

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report here the first transition-metal-catalyzed anti-Markovnikov intermolecular hydroalkoxylation of terminal acetylenes to give enol ethers in high yields without using bases. Arylacetylenes as well as alkenyl- and alkylacetylenes were coupled with aliphatic alcohols, and the products were obtained with high Z selectivity in most cases. Effective catalysts were 8-quinolinolato rhodium complexes, which are structurally simple but have been relatively unexplored as catalysts.

引用

页码：32 / 34

页数：3

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