Multicomponent synthesis of pyrano[2,3-c]coumarins

被引：8
|
作者：
Hsieh, Wan-Chi [1 ]
Lin, Chi-Hui [1 ]
Yang, Yu-Ju [1 ]
Yang, Ding-Yah [1 ]
机构：
[1] Tunghai Univ, Dept Chem, 1727,Sec 4,Taiwan Blvd, Taichung 40704, Taiwan
来源：
RSC ADVANCES | 2018年 / 8卷 / 68期
关键词：
ONE-POT SYNTHESIS; COUMARIN DERIVATIVES; FERULA-COMMUNIS; PYRANOCOUMARINS; 4-HYDROXYCOUMARINS; CONDENSATION; INHIBITORS; PRODUCTS; WATER;
D O I：
10.1039/c8ra06666c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A base-catalyzed, pseudo-four-component reaction of 4-hydroxycoumarin, two molecules of acetone, and amine towards the synthesis of pyrano[2,3-c]coumarins is reported. The mechanism of this multicomponent reaction is proposed. The reaction is further extended to the preparation of coumarin-substituted pyrano[2,3-c]coumarins by a base-catalyzed, pseudo four-component reaction of two molecules of 4-hydroxycoumarin and two molecules of acetone.
引用
收藏
页码：39162 / 39169
页数：8
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