Variably protease-sensitive prionopathy in a PRNP codon 129 heterozygous UK patient with co-existing tau, α synuclein and Aβ pathology

被引：29

作者：

Head, Mark W. ^{[3
]}

Lowrie, Suzanne ^{[3
]}

Chohan, Gurjit ^{[3
]}

Knight, Richard ^{[3
]}

Scoones, David J. ^{[2
]}

Ironside, James W. ^{[1
,3
]}

机构：

[1] Univ Edinburgh, Western Gen Hosp, Natl CJD Surveillance Unit, Edinburgh EH4 2XU, Midlothian, Scotland

[2] James Cook Univ Hosp, Dept Neuropathol, Middlesbrough, Cleveland, England

[3] Univ Edinburgh, Sch Mol & Clin Med, Natl CJD Surveillance Unit, Edinburgh, Midlothian, Scotland

来源：

ACTA NEUROPATHOLOGICA | 2010年 / 120卷 / 06期

基金：

英国医学研究理事会;

关键词：

Protease-sensitive prionopathy; Creutzfeldt-Jakob disease; Prion protein; PRNP codon 129; Alzheimer's disease; Lewy body disease; PRION PROTEIN; DISEASE;

D O I：

10.1007/s00401-010-0766-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：821 / 823

页数：3

共 6 条

[1] STAGING OF ALZHEIMERS-DISEASE-RELATED NEUROFIBRILLARY CHANGES [J].

BRAAK, H ;

BRAAK, E .

NEUROBIOLOGY OF AGING, 1995, 16 (03) :271-278

[2] A novel human disease with abnormal prion protein sensitive to protease [J].

Gambetti, Pierluigi ;

Dong, Zhiqian ;

Yuan, Jue ;

Xiao, Xiangzhu ;

Zheng, Mengjie ;

Alshekhlee, Amer ;

Castellani, Rudy ;

Cohen, Mark ;

Barria, Marcelo A. ;

Gonzalez-Romero, D. ;

Belay, Ermias D. ;

Schonberger, Lawrence B. ;

Marder, Karen ;

Harris, Carrie ;

Burke, James R. ;

Montine, Thomas ;

Wisniewski, Thomas ;

Dickson, Dennis W. ;

Soto, Claudio ;

Hulette, Christine M. ;

Mastrianni, James A. ;

Kong, Qingzhong ;

Zou, Wen-Quan .

ANNALS OF NEUROLOGY, 2008, 63 (06) :697-708

[3] A case of protease sensitive prionopathy in a patient in the UK [J].

Head, M. W. ;

Knight, R. ;

Zeidler, M. ;

Yull, H. ;

Barlow, A. ;

Ironside, J. W. .

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2009, 35 (06) :628-632

[4] The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype [J].

Jansen, C. ;

Head, M. W. ;

van Gool, W. A. ;

Baas, F. ;

Yull, H. ;

Ironside, J. W. ;

Rozemuller, A. J. M. .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2010, 81 (09) :1052-1055

[5] Applicability of current staging/categorization of α-synuclein pathology and their clinical relevance [J].

Parkkinen, Laura ;

Pirttila, Tuula ;

Alafuzoff, Irina .

ACTA NEUROPATHOLOGICA, 2008, 115 (04) :399-407

[6] Variably Protease-Sensitive Prionopathy: A New Sporadic Disease of the Prion Protein [J].

Zou, Wen-Quan ;

Puoti, Gianfranco ;

Xiao, Xiangzhu ;

Yuan, Jue ;

Qing, Luting ;

Cali, Ignazio ;

Shimoji, Miyuki ;

Langeveld, Jan P. M. ;

Castellani, Rudy ;

Notari, Silvio ;

Crain, Barbara ;

Schmidt, Robert E. ;

Geschwind, Michael ;

De Armond, Stephen J. ;

Cairns, Nigel J. ;

Dickson, Dennis ;

Honig, Lawrence ;

Maria Torres, Juan ;

Mastrianni, James ;

Capellari, Sabina ;

Giaccone, Giorgio ;

Belay, Ermias D. ;

Schonberger, Lawrence B. ;

Cohen, Mark ;

Perry, George ;

Kong, Qingzhong ;

Parchi, Piero ;

Tagliavini, Fabrizio ;

Gambetti, Pierluigi .

ANNALS OF NEUROLOGY, 2010, 68 (02) :162-172

← 1 →