Language disorder as a marker for schizophrenia

被引:10
作者
Hartopo, Dhenni [1 ]
Kalalo, Royke Tony [2 ]
机构
[1] Univ Airlangga, Dr Soetomo Gen Acad Hosp, Dept Psychiat, Psychiat Residency Program,Fac Med, Surabaya, Indonesia
[2] Univ Airlangga, Dr Soetomo Gen Acad Hosp, Fac Med, Div Child & Adolescent Psychiat,Dept Psychiat, Jl Mayjend Prof Dr Moestopo 47, Surabaya 60286, East Java, Indonesia
关键词
biomarkers; language disorders; natural language processing; schizophrenia; semantics; THOUGHT; SPEECH; SCALE;
D O I
10.1111/appy.12485
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
A language disorder is a significant symptom of schizophrenia. A psychiatrist can find this disorder when interviews with a patient. Screening and diagnosis in patients with schizophrenia alone rely heavily on interviews conducted on patients and any instructions captured from patients both verbally and nonverbally. A psychiatrist can also analyze the language aspects in schizophrenia from a language level perspective ranging from phonetic to pragmatic. This analysis paves the way for the process of interference detection since the prodromal phase. Language disorder in schizophrenia is often associated with impaired thinking processes. However, with the development of science and technology today, there is an objective and quantitative method of computational analysis of language through the Natural Language Processing process with a semantic space model that allows a psychiatrist to learn aspects of the human language process, especially in semantic and pragmatic aspects. The review provides a groundbreaking proposal for biomarkers for schizophrenia that have not been available so far through the assessment of language disorders in patients with schizophrenia. Objective and accurate detection of language disorders in schizophrenia can be a modality for psychiatrists to screen, make diagnoses, determine prognosis, evaluate therapies, and monitor recurrence using existing technology media.
引用
收藏
页数:6
相关论文
共 29 条
[21]   An introduction to latent semantic analysis [J].
Landauer, TK ;
Foltz, PW ;
Laham, D .
DISCOURSE PROCESSES, 1998, 25 (2-3) :259-284
[22]  
Merriam-Webster I., 2016, MERR WEBST ADV LEARN
[23]   Theranostic Biomarkers for Schizophrenia [J].
Perkovic, Matea Nikolac ;
Erjavec, Gordana Nedic ;
Strac, Dubravka Svob ;
Uzun, Suzana ;
Kozumplik, Oliver ;
Pivac, Nela .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (04)
[24]   Language in schizophrenia and its relationship to formal thought disorder [J].
Rodriguez-Ferrera, S ;
McCarthy, RA ;
McKenna, PJ .
PSYCHOLOGICAL MEDICINE, 2001, 31 (02) :197-205
[25]   Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017 [J].
Roth, Gregory A. ;
Abate, Degu ;
Abate, Kalkidan Hassen ;
Abay, Solomon M. ;
Abbafati, Cristiana ;
Abbasi, Nooshin ;
Abbastabar, Hedayat ;
Abd-Allah, Load ;
Abdela, Jemal ;
Abdelalim, Ahmed ;
Abdollahpour, Ibrahim ;
Abdulkader, Rizwan Suliankatchi ;
Abebe, Haftom Temesgen ;
Abebe, Molla ;
Abebe, Zegeye ;
Abejie, Ayenew Negesse ;
Abera, Semaw F. ;
Abil, Olifan Zewdie ;
Abraha, Haftom Niguse ;
Abrham, Aklilu Roba ;
Abu-Raddad, Laith Jamal ;
Accrombessi, Manfred Mario Kokou ;
Acharya, Dilaram ;
Adamu, Abdu A. ;
Adebayo, Oladimeji ;
Adedoyin, Rufus Adesoji ;
Adekanmbi, Victor ;
Adookunboh, Olatunii ;
Adhena, Beyene Meressa ;
Adib, Mina G. ;
Admasie, Aniha ;
Afshin, Ashkan ;
Agarwal, Gina ;
Agesa, Karelia M. ;
Agrawal, Anurag ;
Agrawal, Sutapa ;
Ahmadi, Alireza ;
Ahmadi, Melidi ;
Ahmed, Muktar Beshir ;
Ahmed, Sayent ;
Aichour, Amani Nidhal ;
Aichour, Ibtihel ;
Aichour, Miloud Taki Fddine ;
Akbari, Mohammad Esmaeil ;
Akinyeniti, Rufus Olusola ;
Akseer, Nadia ;
Al-Aly, Ziyad ;
Al-Eyadhy, Ayman ;
Al-Raddadi, Rajaa M. ;
Alandab, Fares .
LANCET, 2018, 392 (10159) :1736-1788
[26]   VOCAL ALTERATIONS IN SCHIZOPHRENIC SPEECH [J].
STEIN, J .
JOURNAL OF NERVOUS AND MENTAL DISEASE, 1993, 181 (01) :59-62
[27]   Non-verbal speech cues as objective measures for negative symptoms in patients with schizophrenia [J].
Tahir, Yasir ;
Yang, Zixu ;
Chakraborty, Debsubhra ;
Thalmann, Nadia ;
Thalmann, Daniel ;
Maniam, Yogeswary ;
Rashid, Nur Amirah Binte Abdul ;
Tan, Bhing-Leet ;
Keong, Jimmy Lee Chee ;
Dauwels, Justin .
PLOS ONE, 2019, 14 (04)
[28]  
Traxler M. J., 2011, Introduction to psycholinguistics: Understanding language science, V1st
[29]  
Wrobel Janusz., 1989, Language and Schizophrenia