Occupational prestige, social mobility and the association with lung cancer in men

被引：20

作者：

Behrens, Thomas ^{[1
]}

Gross, Isabelle ^{[1
]}

Siemiatycki, Jack ^{[2
,3
]}

Conway, David I. ^{[4
]}

Olsson, Ann ^{[5
,6
]}

Stuecker, Isabelle ^{[7
,8
]}

Guida, Florence ^{[7
,8
]}

Joeckel, Karl-Heinz ^{[9
]}

Pohlabeln, Hermann ^{[10
]}

Ahrens, Wolfgang ^{[10
,11
]}

Brueske, Irene ^{[12
]}

Wichmann, Heinz-Erich ^{[12
,36
]}

Gustavsson, Per ^{[6
]}

Consonni, Dario ^{[13
]}

Merletti, Franco ^{[14
]}

Richiardi, Lorenzo ^{[14
]}

Simonato, Lorenzo ^{[15
]}

Fortes, Cristina ^{[16
]}

Parent, Marie-Elise ^{[17
]}

McLaughlin, John ^{[18
]}

Demers, Paul ^{[18
]}

Landi, Maria Teresa ^{[19
]}

Caporaso, Neil ^{[19
]}

Zaridze, David ^{[20
]}

Szeszenia-Dabrowska, Neonila ^{[21
]}

Rudnai, Peter ^{[22
]}

Lissowska, Jolanta ^{[23
,24
]}

Fabianova, Eleonora ^{[25
]}

Tardon, Adonina ^{[26
]}

Field, John K. ^{[27
,28
]}

Dumitru, Rodica Stanescu ^{[29
]}

Bencko, Vladimir ^{[30
]}

Foretova, Lenka ^{[31
,32
]}

Janout, Vladimir ^{[33
,37
]}

Kromhout, Hans ^{[34
]}

Vermeulen, Roel ^{[34
]}

Boffetta, Paolo ^{[35
]}

Straif, Kurt ^{[5
]}

Schuez, Joachim ^{[5
]}

Hovanec, Jan ^{[1
]}

Kendzia, Benjamin ^{[1
]}

Pesch, Beate ^{[1
]}

Bruening, Thomas ^{[1
]}

机构：

[1] Inst Ruhr Univ Bochum, Inst Prevent & Occupat Med German Social Accident, Brkle de La Camp Pl 1, D-44789 Bochum, Germany

[2] Univ Montreal, Hosp Res Ctr CRCHUM, Montreal, PQ, Canada

[3] Univ Montreal, Sch Publ Hlth, Montreal, PQ, Canada

[4] Univ Glasgow, Sch Dent, Coll Med Vet & Life Sci, Glasgow G2 3JZ, Lanark, Scotland

[5] IARC, Lyon, France

[6] Karolinska Inst, Inst Environm Med, Stockholm, Sweden

[7] INSERM, Ctr Res Epidemiol & Populat Hlth CESP, F-94807 Villejuif, France

[8] Univ Paris 11, UMRS 1018, F-94807 Villejuif, France

[9] Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany

[10] Leibniz Inst Prevent Res & Epidemiol BIPS GmbH, Bremen, Germany

[11] Univ Bremen, Inst Stat, Bremen, Germany

[12] Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany

[13] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy

[14] Univ Turin, Dept Med Sci, Canc Epidemiol Unit, Turin, Italy

[15] Univ Padua, Dept Mol Med, Lab Publ Hlth & Populat Studies, Padua, Italy

[16] Ist Dermopatico Immacolata, Epidemiol Unit, Rome, Italy

[17] Univ Quebec, INRS Inst Armand Frappier, Laval, PQ, Canada

[18] Canc Care Ontario, Occupat Canc Res Ctr, Toronto, ON, Canada

[19] NCI, Div Canc Epidemiol & Genet, Bethesda, MD USA

[20] Russian Canc Res Ctr, Inst Carcinogenesis, Moscow, Russia

[21] Nofer Inst Occupat Med, Lodz, Poland

[22] Natl Ctr Publ Hlth, Budapest, Hungary

[23] M Sklodowska Curie Canc Ctr, Warsaw, Poland

[24] Inst Oncol, Warsaw, Poland

[25] Prevent Occupat Med, Reg Author Publ Hlth, Banska Bystrica, Slovakia

[26] Univ Oviedo Ciber Epidemiol, CIBERESP, Mol Epidemiol Canc Unit, Oviedo, Spain

[27] Univ Liverpool, Canc Res Ctr, Roy Castle Lung Canc Res Programme, Liverpool, Merseyside, England

[28] Univ Liverpool, Inst Translat Med, Dept Mol & Clin Canc Med, Liverpool, Merseyside, England

[29] Natl Inst Publ Hlth, Bucharest, Romania

[30] Charles Univ Prague, Fac Med 1, Inst Hyg & Epidemiol, Prague, Czech Republic

[31] Masaryk Univ, Masaryk Mem Canc Inst, Dept Canc Epidemiol & Genet, Brno, Czech Republic

[32] Masaryk Univ, Fac Med, Brno, Czech Republic

[33] Palacky Univ, Fac Med, Olomouc, Czech Republic

[34] Univ Utrecht, Inst Risk Assessment Sci, Environm Epidemiol Div, Utrecht, Netherlands

[35] Icahn Sch Med Mt Sinai, Inst Canc, New York, NY USA

[36] Icahn Sch Med Mt Sinai, Inst Translat Epidemiol, New York, NY USA

[37] Tech Univ Munich, Inst Med Stat & Epidemiol, Munich, Germany

来源：

BMC CANCER | 2016年 / 16卷

基金：

加拿大健康研究院;

关键词：

Life course; Occupational history; Social prestige; Socio-economic status; SYNERGY; Transitions; SOCIOECONOMIC-STATUS; EDUCATIONAL INEQUALITIES; HEALTH RESEARCH; LIFE-COURSE; RISK; INDICATORS; POSITION; SMOKING; DISPARITIES; CONTRIBUTE;

D O I：

10.1186/s12885-016-2432-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: The nature of the association between occupational social prestige, social mobility, and risk of lung cancer remains uncertain. Using data from the international pooled SYNERGY case-control study, we studied the association between lung cancer and the level of time-weighted average occupational social prestige as well as its lifetime trajectory. Methods: We included 11,433 male cases and 14,147 male control subjects. Each job was translated into an occupational social prestige score by applying Treiman's Standard International Occupational Prestige Scale (SIOPS). SIOPS scores were categorized as low, medium, and high prestige (reference). We calculated odds ratios (OR) with 95 % confidence intervals (CI), adjusting for study center, age, smoking, ever employment in a job with known lung carcinogen exposure, and education. Trajectories in SIOPS categories from first to last and first to longest job were defined as consistent, downward, or upward. We conducted several subgroup and sensitivity analyses to assess the robustness of our results. Results: We observed increased lung cancer risk estimates for men with medium (OR = 1.23; 95 % CI 1.13-1.33) and low occupational prestige (OR = 1.44; 95 % CI 1.32-1.57). Although adjustment for smoking and education reduced the associations between occupational prestige and lung cancer, they did not explain the association entirely. Traditional occupational exposures reduced the associations only slightly. We observed small associations with downward prestige trajectories, with ORs of 1.13, 95 % CI 0.88-1.46 for high to low, and 1.24; 95 % CI 1.08-1.41 for medium to low trajectories. Conclusions: Our results indicate that occupational prestige is independently associated with lung cancer among men.

引用

页数：12

共 36 条

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