Endolymphatic Sac Tumor Showing Increased Activity on 68Ga DOTATATE PET/CT

被引：17
|
作者：
Papadakis, Georgios Z. [1 ]
Millo, Corina [2 ]
Sadowski, Samira M. [3 ,4 ]
Bagci, Ulas [5 ]
Patronas, Nicholas J. [1 ]
机构：
[1] NCI, Radiol & Imaging Sci, Warren Grant Magnuson Clin Ctr, NIH, Bethesda, MD 20892 USA
[2] NCI, Div Nucl Med, RAD&IS, Ctr Clin,NIH, Bethesda, MD 20892 USA
[3] NCI, Endocrine Oncol Branch, NIH, Bethesda, MD 20892 USA
[4] Univ Hosp Geneva, Endocrine & Thorac Surg, Geneva, Switzerland
[5] Univ Cent Florida, Dept Elect & Comp Sci, Ctr Comp Vis Res, Orlando, FL 32816 USA
来源：
CLINICAL NUCLEAR MEDICINE | 2016年 / 41卷 / 10期
关键词：
endolymphatic sac tumors; von Hippel-Lindau disease; Ga-68-DOTATATE PET/CT; somatostatin receptors-imaging; HIPPEL-LINDAU-DISEASE;
D O I：
10.1097/RLU.0000000000001315
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Endolymphatic sac tumors (ELSTs) are rare tumors arising from the epithelium of the endolymphatic sac and duct that can be either sporadic or associated with von Hippel-Lindau (VHL) disease. We report a case of a VHL patient with histologically proven residual ELST who underwent Ga-68 DOTATATE PET/CT showing increased activity (SUVmax, 6.29) by the ELST. The presented case of a VHL-associated ELST with increased Ga-68 DOTATATE uptake indicates cell-surface expression of somatostatin receptors by this tumor, suggesting the potential application of somatostatin receptor imaging using Ga-68 DOTA-conjugated peptides in the workup and management of these patients.
引用
收藏
页码：783 / 784
页数：2
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