Rapid detection of blaOXA in carbapenem-susceptible Acinetobacter radioresistens bacteremia leading to unnecessary antimicrobial administration

被引：7
|
作者：
Brady, Adam C. [1 ]
Lewis, James S., II [2 ]
Pfeiffer, Christopher D. [1 ,3 ]
机构：
[1] Oregon Hlth & Sci Univ, Dept Med, Div Infect Dis, Portland, OR 97201 USA
[2] Oregon Hlth & Sci Univ, Dept Pharm, Portland, OR 97201 USA
[3] VA Portland Hlth Care Syst, Portland, OR USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2016年 / 85卷 / 04期
关键词：
Rapid diagnostics; Molecular diagnostics; Acinetobacter; Carbapenemase; Bacteremia; IDENTIFICATION; RESISTANCE;
D O I：
10.1016/j.diagmicrobio.2016.04.025
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Rapid molecular techniques to identify resistant pathogens are revolutionizing antibiotic stewardship; however, it is important to recognize the limitations of these techniques. Herein we describe two cases of bacteremia that were both initially identified by genotypic testing as carbapenem-resistant Acinetobacter spp. and subsequently identified phenotypically as carbapenem-susceptible A. radioresistens. The genotypic results prompted unnecessary broad-spectrum antibiotic use and infection control concerns. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码：488 / 489
页数：2
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