Assessment of Fatigue in Cancer Patients and Community Dwellers: Validation Study of the Filipino Version of the Brief Fatigue Inventory

Objective: Clinical trials that might identify effective therapies for cancer-related fatigue, one of the most distressing symptoms experienced by patients, require a validated fatigue assessment tool. We developed and validated a Filipino language version of the Brief Fatigue Inventory (BFI-F) for describing the prevalence and severity of fatigue among Filipino patients with cancer. Methods: We conducted a cross-sectional study in Manila, Philippines, in 206 patients with cancer and 170 age-matched community-dwelling adults who had never had a diagnosis of cancer. Validity and reliability were evaluated by principal factor analysis and Cronbach's alpha coefficients. Results: Factor analysis extracted 1 factor, i.e. fatigue severity, with a Cronbach's alpha of 0.95; this is consistent with the original BFI English version validation study. Approximately 49% of the patients with cancer had mild fatigue, 34% had moderate fatigue, and 17% had severe fatigue. Patients with a poorer performance status had significantly worse fatigue than patients with a better perfor-mance status (5.0 +/- 2.8 vs. 3.8 +/- 2.2; p < 0.05). Compared with community adults, the patients with cancer reported significantly higher levels of fatigue. Conclusions: The BFI-F had satisfactory internal consistency and validity, and it was able to measure the severity of fatigue and its influence on Filipino cancer patients. Copyright (C) 2010 S. Karger AG, Basel