Identification of a progenitor of the CTX-M-9 group of extended-spectrum β-lactamases from Kluyvera georgiana isolated in Guyana

被引：92
作者：
Olson, AB
Silverman, M
Boyd, DA
McGeer, A
Willey, BM
Pong-Porter, V
Daneman, N
Mulvey, MR
机构：
[1] Natl Microbiol Lab, Winnipeg, MB R3E 3R2, Canada
[2] Univ Manitoba, Winnipeg, MB, Canada
[3] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 05期
关键词：
D O I：
10.1128/AAC.49.5.2112-2115.2005
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Chromosomal beta-lactamase genes (bla(KLUY)) from six Kluyvera georgiana strains isolated in Guyana were cloned and expressed in Escherichia coli. KLUY-1 exhibited 100% amino acid identity with the extended-spectrum beta-lactamase CTX-M-14. We also show that a 2.7-kb Kluyvera chromosomal region exhibits 99% nucleotide identity to a portion of In60 that includes bla(CTX-M-9).
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页码：2112 / 2115
页数：4
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