NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

被引：8
作者：
Behara, Krishna Kalyani [1 ]
Rajesh, Y. [2 ]
Chaudhuri, Amrita [1 ]
Gangopadhyay, Moumita [1 ]
Mandal, Mahitosh [2 ]
Singh, N. D. Pradeep [1 ]
机构：
[1] Indian Inst Technol IIT Kharagpur, Dept Chem, Kharagpur 721302, W Bengal, India
[2] Indian Inst Technol Kharagpur, Sch Med Sci & Technol, Kharagpur 721302, W Bengal, India
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2018年 / 6卷 / 38期
关键词：
ANTICANCER DRUG-RELEASE; POLYMER NANOPARTICLES; STERILIZATION; PHOTOTHERAPY; NANOHYBRIDS; EMISSION; THERAPY; AGENT; DNA;
D O I：
10.1039/c8tb01209a
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Nitric oxide photodonor (NOD) conjugated perylene tetracarboxylate ester (TPT) based fluorescent organic TPT(NOD)(4) nanoparticles (NPs) with aggregation induced NIR emission have shown photoinduced nitric oxide delivery along with a red to green emission transition. Time dependent imaging and dose dependent cytotoxicity studies of these NPs using U87MG cells demonstrate the self monitoring and real time reporting abilities and potential anticancer activity of the system, respectively.
引用
收藏
页码：6042 / 6046
页数：5
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