Asymmetric reduction of 2-Oxo-4-phenylbutanoic acid ethyl ester by Daucus carota cell cultures

被引:46
作者
Chadha, A [1 ]
Manohar, M [1 ]
Soundararajan, T [1 ]
Lokeswari, TS [1 ]
机构
[1] SPIC SCI FDN, DIV BIOTECHNOL, MADRAS 600032, TAMIL NADU, INDIA
关键词
D O I
10.1016/0957-4166(96)00183-8
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A novel method to produce (R)-(-)-2-hydroxy-4-phenylbutanoic acid ethyl ester 1b has been developed. 2-Oxo-4-phenylbutanoic acid ethyl ester 1a is reduced to 1b by the cell cultures of Daucus carota in high enantiomeric excess and yield. (C) 1996 Elsevier Science Ltd
引用
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页码:1571 / 1572
页数:2
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