Prospective cohort study into post-disaster benzodiazepine use demonstrated only short-term increase

被引:11
作者
Dorn, T. [1 ]
Yzermans, C. J. [1 ]
van der Zee, J. [1 ]
机构
[1] Netherlands Inst Hlth Serv Res, NIVEL, NL-3500 BN Utrecht, Netherlands
关键词
benzodiazepines; stress; psychological; life change events; cohort studies; disasters; family; medical records systems; computerized;
D O I
10.1016/j.jclinepi.2006.10.023
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Objectives: Benzodiazepines are typically prescribed for anxiety and insomnia, two complaints often reported after disasters. Benzodiazepines can cause mental or physical dependence, especially when taken for a long time. This study aims at evaluating benzodiazepine use in a disaster-stricken community with the help of computer-based records. Study Design and Setting: This prospective cohort study covers a period of 4 years. For every patient, predisaster baseline data are available. Multilevel regression is applied to study differences in benzodiazepine use in 496 patients whose children were involved in the Volendam cafe fire on January 1, 2001 compared with 1,709 community controls, and 4,530 patients from an unaffected cohort. Results: In community controls and patients from the unaffected cohort, benzodiazepine use remained stable in the course of the years. In the first year postfire, parents of disaster victims were 1.58 times more likely to use benzodiazepines than community controls (95% confidence interval 1.13-2.23). With regard to long-term use, differences between community controls and parents were statistically nonsignificant. Conclusions: In the studied community, benzodiazepines were predominantly prescribed as a short-term intervention. Clinical guidelines that advocate a conservative prescription policy were well adhered to. (C) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:795 / 802
页数:8
相关论文
共 44 条
[1]  
[Anonymous], ROLE GEN PRACTICE PR
[2]  
[Anonymous], BURNOUT FAMILIES SYS
[3]   UNEXPECTED CHILDHOOD DEATH - POSTTRAUMATIC-STRESS-DISORDER IN SURVIVING SIBLINGS AND PARENTS [J].
APPLEBAUM, DR ;
BURNS, GL .
JOURNAL OF CLINICAL CHILD PSYCHOLOGY, 1991, 20 (02) :114-120
[4]   GUIDELINES FOR THE RATIONAL USE OF BENZODIAZEPINES - WHEN AND WHAT TO USE [J].
ASHTON, H .
DRUGS, 1994, 48 (01) :25-40
[5]   Misclassification of exposure is high when interview data on drug use are used as a proxy measure of chronic drug use during follow-up [J].
Beiderbeck, AB ;
Sturkenboom, MCJM ;
Coebergh, JWW ;
Leufkens, HGM ;
Stricker, BHC .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2004, 57 (09) :973-977
[6]   REVIEW OF PSYCHIATRIC EPIDEMIOLOGIC RESEARCH ON DISASTERS [J].
BROMET, E ;
DEW, MA .
EPIDEMIOLOGIC REVIEWS, 1995, 17 (01) :113-119
[7]   Shared help seeking behaviour within families: a retrospective cohort study [J].
Cardol, M ;
Groenewegen, PP ;
de Bakker, DH ;
Spreeuwenberg, P ;
van Dijk, L ;
van den Bosch, W .
BMJ-BRITISH MEDICAL JOURNAL, 2005, 330 (7496) :882-884B
[8]   The use of routinely collected computer data for research in primary care: opportunities and challenges [J].
de Lusignan, S ;
van Weel, C .
FAMILY PRACTICE, 2006, 23 (02) :253-263
[9]   Disaster-related stress as a prospective risk factor for hypertension in parents of adolescent fire victims [J].
Dorn, Tina ;
Yzermans, C. Joris ;
Guijt, Henk ;
van der Zee, Jouke .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2007, 165 (04) :410-417
[10]   Disaster and subsequent healthcare utilization - A longitudinal study among victims, their family members, and control subjects [J].
Dorn, Tina ;
Yzermans, C. Joris ;
Kerssens, Jan J. ;
Spreeuwenberg, Peter M. M. ;
van der Zee, Jouke .
MEDICAL CARE, 2006, 44 (06) :581-589