How I Treat Cryptococcosis in Organ Transplant Recipients

被引：23

作者：

Singh, Nina ^{[1
,2
]}

机构：

[1] VA Pittsburgh Healthcare Syst, Dept Med, Div Infect Dis, Pittsburgh, PA USA

[2] Univ Pittsburgh, Pittsburgh, PA USA

来源：

TRANSPLANTATION | 2012年 / 93卷 / 01期

关键词：

Fungal infection; Cryptococcus; Transplant; RECONSTITUTION INFLAMMATORY SYNDROME; VERSUS-HOST-DISEASE; AMPHOTERICIN-B; NEOFORMANS INFECTION; SOLID-ORGAN; PULMONARY CRYPTOCOCCOSIS; FUNGAL-INFECTIONS; ANTIFUNGAL AGENTS; RENAL-ALLOGRAFT; INTESTINAL TRANSPLANTATION;

D O I：

10.1097/TP.0b013e318236cd1a

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cryptococcosis is a significant opportunistic mycoses in organ transplant recipients. Topical developments in the field in the past few years have highlighted important issues and at the same time raised new questions regarding the management of this yeast. These include, for example, management of pretransplant cryptococcosis during transplant candidacy and timing of transplant in these instances; potential for donor transmission of cryptococcosis in light of recent fatal transmissions; and prevention and treatment of Cryptococcus-associated immune reconstitution syndrome. Discussed herein are challenges posed by these issues and evidence-based data to optimize the management of posttransplant cryptococcosis.

引用

页码：17 / 21

页数：5

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