Design and implementation of a high-throughput biological sample processing facility using modern manufacturing principles

被引：33

作者：

Downey, Paul ^{[1
]}

Peakman, Tim C. ^{[1
]}

机构：

[1] UK Biobank, Stockport SK3 0SA, Cheshire, England

来源：

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY | 2008年 / 37卷

基金：

英国医学研究理事会;

关键词：

design and implementation of a Biobank; high throughput biological sample processing and archiving;

D O I：

10.1093/ije/dyn031

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research. Methods Modem manufacturing principles were used to direct the development of the sample processing facility and automated systems. Results A fit for purpose facility comprising technology, systems, dedicated process, infrastructure and an appropriate staff structure has been implemented that will deliver and maintain a resource that will support the long-term goals of the UK Biobank study. Conclusions Modern manufacturing principles are appropriate for use in the development of a high throughput biological sample processing facility.

引用

页码：46 / 50

页数：5

共 7 条

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[Anonymous], ENG STAT HDB

[2]

[Anonymous], FAILURE MODE EFFECTS

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