Ensembl Genomes 2020-enabling non-vertebrate genomic research

被引：311

作者：

Howe, Kevin L. ^{[1
]}

Contreras-Moreira, Bruno ^{[1
]}

De Silva, Nishadi ^{[1
]}

Maslen, Gareth ^{[1
]}

Akanni, Wasiu ^{[1
]}

Allen, James ^{[1
]}

Alvarez-Jarreta, Jorge ^{[1
]}

Barba, Matthieu ^{[1
]}

Bolser, Dan M. ^{[1
]}

Cambell, Lahcen ^{[1
]}

Carbajo, Manuel ^{[1
]}

Chakiachvili, Marc ^{[1
]}

Christensen, Mikkel ^{[1
]}

Cummins, Carla ^{[1
]}

Cuzick, Alayne ^{[2
]}

Davis, Paul ^{[1
]}

Fexova, Silvie ^{[1
]}

Gall, Astrid ^{[1
]}

George, Nancy ^{[1
]}

Gil, Laurent ^{[1
]}

Gupta, Parul ^{[3
]}

Hammond-Kosack, Kim E. ^{[2
]}

Haskell, Erin ^{[1
]}

Hunt, Sarah E. ^{[1
]}

Jaiswal, Pankaj ^{[3
]}

Janacek, Sophie H. ^{[1
]}

Kersey, Paul J. ^{[1
]}

Langridge, Nick ^{[1
]}

Maheswari, Uma ^{[1
]}

Maurel, Thomas ^{[1
]}

McDowall, Mark D. ^{[1
]}

Moore, Ben ^{[1
]}

Muffato, Matthieu ^{[1
]}

Naamati, Guy ^{[1
]}

Naithani, Sushma ^{[3
]}

Olson, Andrew ^{[4
]}

Papatheodorou, Irene ^{[1
]}

Patricio, Mateus ^{[1
]}

Paulini, Michael ^{[1
]}

Pedro, Helder ^{[1
]}

Perry, Emily ^{[1
]}

Preece, Justin ^{[3
]}

Rosello, Marc ^{[1
]}

Russell, Matthew ^{[1
]}

Sitnik, Vasily ^{[1
]}

Staines, Daniel M. ^{[1
]}

Stein, Joshua ^{[4
]}

Tello-Ruiz, Marcela K. ^{[4
]}

Trevanion, Stephen J. ^{[1
]}

Urban, Martin ^{[2
]}

机构：

[1] European Bioinformat Inst, European Mol Biol Lab, Wellcome Genome Campus, Cambridge CB10 1SD, England

[2] Rothamsted Res, Dept Biointeract & Crop Protect, Harpenden AL5 2JQ, Herts, England

[3] Oregon State Univ, Dept Bot & Plant Pathol, Corvallis, OR 97331 USA

[4] Cold Spring Harbor Lab, 1 Bungtown Rd, Cold Spring Harbor, NY 11724 USA

[5] ARS, USDA, NAA Robert W Holley Ctr Agr & Hlth, Ithaca, NY 14853 USA

来源：

NUCLEIC ACIDS RESEARCH | 2020年 / 48卷 / D1期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会; 美国国家卫生研究院; 英国惠康基金; 欧盟地平线“2020”; 美国国家科学基金会; 美国农业部;

关键词：

D O I：

10.1093/nar/gkz890

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of interfaces to genomic data across the tree of life, including reference genome sequence, gene models, transcriptional data, genetic variation and comparative analysis. Data may be accessed via our website, online tools platform and programmatic interfaces, with updates made four times per year (in synchrony with Ensembl). Here, we provide an overview of Ensembl Genomes, with a focus on recent developments. These include the continued growth, more robust and reproducible sets of orthologues and paralogues, and enriched views of gene expression and gene function in plants. Finally, we report on our continued deeper integration with the Ensembl project, which forms a key part of our future strategy for dealing with the increasing quantity of available genome-scale data across the tree of life.

引用

页码：D689 / D695

页数：7

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