Granulosa Cell Tumors of the Ovary and Inhibin B

被引：7

作者：

Lyubimova, N. V. ^{[1
]}

Beyshembaev, A. M. ^{[1
]}

Kushlinskiy, D. N. ^{[2
]}

Zordania, K. I. ^{[2
]}

Adamyan, L. V. ^{[2
]}

机构：

[1] Russian Acad Med Sci, NN Blokhin Canc Res Ctr, Moscow, Russia

[2] Moscow State Univ Med & Dent, Dept Reprod Med & Surg, Postgrad Educ Fac, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2011年 / 150卷 / 05期

关键词：

inhibin B; granulosa cell tumors of the ovary; relapses; SERUM INHIBIN; WOMEN;

D O I：

10.1007/s10517-011-1209-z

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We present the results of immunoenzyme detection of inhibin B in blood serum of patients with adult-type granulosa cell tumors of the ovary. Blood concentration of inhibin B at the end of menstrual cycle in patients with tumor relapse was significantly higher than in patients during remission and in virtually healthy women. The increase in inhibin B concentration preceded clinical manifestation of the disease relapse by 2-13 months, which demonstrates high diagnostic sensitivity of this marker and suggests that it can be recommended for the use in diagnostics and monitoring of granulosa cell tumors of the ovaries.

引用

页码：635 / 638

页数：4

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