Thermodynamic and spectroscopic interpretation of molecular interactions of nicotine plus alcohol binary mixtures

Density rho, viscosity eta and refractive index n(D) have been experimentally measured for four binary mixtures nicotine + 1-butanol, nicotine + 2-butanol, nicotine + 1,2-propanediol and nicotine + 1,3-propanediol over the temperature range T = (293.15-323.15) K with temperature step 5 K and at atmospheric pressure. Excess molar volumes V-E, viscosity deviations Delta eta, deviations in refractive index Delta n(D), excess Gibbs free energy of activation of viscous flow Delta G*(E), thermal expansion coefficients a, excess thermal expansion coefficients alpha(E), partial molar volumes (V) over bar (i), excess partial molar volumes (V) over bar (E)(i) and it's values at infinite dilutions (V) over bar (E,infinity)(i) were calculated from experimental data and used to analyze non-ideal behavior of mixtures. Fourier-transform infrared analysis of binary mixtures and corresponding pure components was performed at 298.15 K in order to gain insight into the molecular structure of mixtures and possible intermolecular interactions. Performed infra-red analysis confirms the presence of hydrogen bonding between unlike compounds, except for the system nicotine + 1-butanol. Here, the non-ideal behavior of mixtures is contributed to strong intermolecular interaction or in the case of nicotine + 1-butanol due to geometrical packing or dispersion forces of different species. (C) 2016 Elsevier Ltd.