Some aspects of quantum dot toxicity

被引:189
作者
Bottrill, Melanie [1 ]
Green, Mark [1 ]
机构
[1] Kings Coll London, Dept Phys, London WC2R 2LS, England
关键词
LONG-TERM; CDSE NANOCRYSTALS; SIZE SERIES; INDUCED DNA; NANOPARTICLES; CYTOTOXICITY; SKIN; CDTE; CADMIUM; DAMAGE;
D O I
10.1039/c1cc10692a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Quantum dot toxicity has become a hot topic in recent years due to the emergence of semiconductor nanoparticles as highly efficient biological imaging agents. The use of quantum dots in biology is arguably the most successful application of pure nanotechnology in recent times, although unfortunately, the most useful semiconductor particles contain elements that are often thought to be detrimental to health and the environment. In this article, we explore some key reports on this issue.
引用
收藏
页码:7039 / 7050
页数:12
相关论文
共 75 条
  • [1] Nanocrystal targeting in vivo
    Åkerman, ME
    Chan, WCW
    Laakkonen, P
    Bhatia, SN
    Ruoslahti, E
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (20) : 12617 - 12621
  • [2] Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols
    Aldana, J
    Wang, YA
    Peng, XG
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (36) : 8844 - 8850
  • [3] Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots
    Anas, AbdulAziz
    Akita, Hidetaka
    Harashima, Hideyoshi
    Itoh, Tamitake
    Ishikawa, Mitsuru
    Biju, Vasudevanpillai
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2008, 112 (32) : 10005 - 10011
  • [4] Metallothioneins initiate semiconducting nanoparticle cellular toxicity
    Aryal, Baikuntha P.
    Neupane, Kosh R.
    Sandros, Marinella G.
    Benson, David E.
    [J]. SMALL, 2006, 2 (10) : 1159 - 1163
  • [5] Quantum dot anti-CD conjugates: Are they potential photosensitizers or potentiators of classical photosensitizing agents in photodynamic therapy of cancer?
    Bakalova, R
    Ohba, H
    Zhelev, Z
    Nagase, T
    Jose, R
    Ishikawa, M
    Baba, Y
    [J]. NANO LETTERS, 2004, 4 (09) : 1567 - 1573
  • [6] Noninvasive imaging of quantum dots in mice
    Ballou, B
    Lagerholm, BC
    Ernst, LA
    Bruchez, MP
    Waggoner, AS
    [J]. BIOCONJUGATE CHEMISTRY, 2004, 15 (01) : 79 - 86
  • [7] Cadmium, gene regulation, and cellular signalling in mammalian cells
    Beyersmann, D
    Hechtenberg, S
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1997, 144 (02) : 247 - 261
  • [8] Semiconductor nanocrystals as fluorescent biological labels
    Bruchez, M
    Moronne, M
    Gin, P
    Weiss, S
    Alivisatos, AP
    [J]. SCIENCE, 1998, 281 (5385) : 2013 - 2016
  • [9] Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak
    Brunk, UT
    Svensson, I
    [J]. REDOX REPORT, 1999, 4 (1-2) : 3 - 11
  • [10] Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts
    Brunk, UT
    Dalen, H
    Roberg, K
    Hellquist, HB
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 1997, 23 (04) : 616 - 626