Lithium bromide as an efficient, green, and inexpensive catalyst for the synthesis of quinoxaline derivatives at room temperature

被引：18

作者：

Hasaninejad, Alireza ^{[1
]}

Zare, Abdolkarim ^{[2
]}

Mohammadizadeh, Mohammad Reza ^{[1
]}

Shekouhy, Mohsen ^{[1
]}

机构：

[1] Persian Gulf Univ, Fac Sci, Dept Chem, Bushehr 75169, Iran

[2] Payame Noor Univ PNU, Dept Chem, Tehran, Iran

来源：

GREEN CHEMISTRY LETTERS AND REVIEWS | 2010年 / 3卷 / 02期

关键词：

lithium bromide (LiBr); quinoxaline; 1,2-diamine; 1,2-diketone; green chemistry; SOLVENT-FREE CONDITIONS; REUSABLE CATALYST; HIGHLY EFFICIENT; FACILE SYNTHESIS; REGIOSELECTIVE SYNTHESIS; BIOLOGICAL EVALUATION; ORGANIC-REACTIONS; ADDITION-REACTION; MICHAEL ADDITION; ANTITUMOR AGENT;

D O I：

10.1080/17518251003619192

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient, simple, and green procedure for the synthesis of quinoxaline derivatives is described. The condensation of 1,2-diamines with 1,2-diketones using lithium bromide (LiBr) in H(2)O/EtOH as a green reaction media at room temperature affords the title compounds in high to excellent yields and in short reaction times. [GRAPHICS] .

引用

页码：143 / 148

页数：6

共 48 条

[1] Direct and catalytic synthesis of quinoxaline derivatives from epoxides and ene-1,2-diamines
Antoniotti, S
Duñach, E
[J]. TETRAHEDRON LETTERS, 2002, 43 (22) : 3971 - 3973
[2] Synthesis and antimicrobial activity of novel quinoxaline derivatives
Badran, Mohga M.
Moneer, Ashraf A.
Refaat, Hanan M.
El-Malah, Afaf A.
[J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2007, 54 (02) : 469 - 478
[3] The Biginelli condensation:: A novel and efficient regioselective synthesis of dihydropyrimidin-2(1H)-ones using lithium bromide
Baruah, PP
Gadhwal, S
Prajapati, D
Sandhu, JS
[J]. CHEMISTRY LETTERS, 2002, (10) : 1038 - 1039
[4] Chemoselective O-methylation of phenols under non-aqueous condition
Basak, A
Nayak, MK
Chakraborti, AK
[J]. TETRAHEDRON LETTERS, 1998, 39 (27) : 4883 - 4886
[5] An efficient protocol for the synthesis of quinoxaline derivatives at room temperature using molecular iodine as the catalyst
Bhosale, RS
Sarda, SR
Ardhapure, SS
Jadhav, WN
Bhusare, SR
Pawar, RP
[J]. TETRAHEDRON LETTERS, 2005, 46 (42) : 7183 - 7186
[6] Chemoselective protection of carboxylic acid as methyl ester: A practical alternative to diazomethane protocol
Chakraborti, AK
Basak, A
Grover, V
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (21) : 8014 - 8017
[7] Green Chemistry: challenges and opportunities
Clark, JH
[J]. GREEN CHEMISTRY, 1999, 1 (01) : 1 - 8
[8] A recyclable and highly effective sulfamic acid/MeOH catalytic system for the synthesis of quinoxalines at room temperature
Darabi, Hossein Reza
Mohandessi, Shabnam
Aghapoor, Kioumars
Mohsenzadeh, Farshid
[J]. CATALYSIS COMMUNICATIONS, 2007, 8 (03) : 389 - 392
[9] Lithium trifluoromethanesulfonate (LiOTf) as a highly efficient catalyst for chemoselective dithioacetalization of carbonyl compounds under neutral and solvent-free conditions
Firouzabadi, H
Karimi, B
Eslami, S
[J]. TETRAHEDRON LETTERS, 1999, 40 (21) : 4055 - 4058
[10] Firouzabadi H, 1999, SYNTHESIS-STUTTGART, P58

← 1 2 3 4 5 →