VHL-MEDIATED UBIQUITINATION OF THE KINASE MPS1 REGULATES THE MITOTIC CHECKPOINT IN CLEAR CELL RENAL CELL CARCINOMA

被引:0
|
作者
Woodford, Mark
Backe, Sarah
Sager, Rebecca
Shapiro, Oleg
Nsouli, Imad
Wengert, Laura
Bratslavsky, Gennady
Bourboulia, Dimitra
Mollapour, Mehdi
机构
来源
JOURNAL OF UROLOGY | 2022年 / 207卷 / 05期
关键词
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
PD01-01
引用
收藏
页码:E30 / E30
页数:1
相关论文
共 50 条
  • [21] Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma
    Hu, Junhui
    Tan, Ping
    Ishihara, Moe
    Bayley, Nicholas A.
    Schokrpur, Shiruyeh
    Reynoso, Jeremy G.
    Zhang, Yangjun
    Lim, Raymond J.
    Dumitras, Camelia
    Yang, Lu
    Dubinett, Steven M.
    Jat, Parmjit S.
    Van Snick, Jacques
    Huang, Jiaoti
    Chin, Arnold I.
    Prins, Robert M.
    Graeber, Thomas G.
    Xu, Hua
    Wu, Lily
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 8 (01)
  • [22] VHL mutations are associated with increased expression of VHL and ubiquitin in clear cell renal cell carcinoma.
    Hughson, M
    He, Z
    Liu, S
    Shingleton, WB
    LABORATORY INVESTIGATION, 2001, 81 (01) : 111A - 111A
  • [23] Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma
    Junhui Hu
    Ping Tan
    Moe Ishihara
    Nicholas A. Bayley
    Shiruyeh Schokrpur
    Jeremy G. Reynoso
    Yangjun Zhang
    Raymond J. Lim
    Camelia Dumitras
    Lu Yang
    Steven M. Dubinett
    Parmjit S. Jat
    Jacques Van Snick
    Jiaoti Huang
    Arnold I. Chin
    Robert M. Prins
    Thomas G. Graeber
    Hua Xu
    Lily Wu
    Signal Transduction and Targeted Therapy, 8
  • [24] VHL mutations are associated with increased expression of VHL and ubiquitin in clear cell renal cell carcinoma.
    Hughson, M
    He, Z
    Liu, S
    Shingleton, WB
    MODERN PATHOLOGY, 2001, 14 (01) : 111A - 111A
  • [25] FOXD1 regulates cell division in clear cell renal cell carcinoma
    Bond, Kyle H.
    Fetting, Jennifer L.
    Lary, Christine W.
    Emery, Ivette F.
    Oxburgh, Leif
    BMC CANCER, 2021, 21 (01)
  • [26] FOXD1 regulates cell division in clear cell renal cell carcinoma
    Kyle H. Bond
    Jennifer L. Fetting
    Christine W. Lary
    Ivette F. Emery
    Leif Oxburgh
    BMC Cancer, 21
  • [27] VHL regulates the sensitivity of clear cell renal cell carcinoma to SIRT4-mediated metabolic stress via HIF-1α/HO-1 pathway
    Ying Tong
    Jinyan Kai
    Shuo Wang
    Yiwen Yu
    Suhong Xie
    Hui Zheng
    Yanchun Wang
    Yixuan Liu
    Keyu Zhu
    Xiaolin Guan
    Lin Guo
    Renquan Lu
    Cell Death & Disease, 12
  • [28] VHL regulates the sensitivity of clear cell renal cell carcinoma to SIRT4-mediated metabolic stress via HIF-1α/HO-1 pathway
    Tong, Ying
    Kai, Jinyan
    Wang, Shuo
    Yu, Yiwen
    Xie, Suhong
    Zheng, Hui
    Wang, Yanchun
    Liu, Yixuan
    Zhu, Keyu
    Guan, Xiaolin
    Guo, Lin
    Lu, Renquan
    CELL DEATH & DISEASE, 2021, 12 (07)
  • [29] VHL suppresses RAPTOR and inhibits mTORC1 signaling in clear cell renal cell carcinoma
    Athina Ganner
    Christina Gehrke
    Marinella Klein
    Lena Thegtmeier
    Tanja Matulenski
    Laura Wingendorf
    Lu Wang
    Felicitas Pilz
    Lars Greidl
    Lisa Meid
    Fruzsina Kotsis
    Gerd Walz
    Ian J. Frew
    Elke Neumann-Haefelin
    Scientific Reports, 11
  • [30] Targeting the mitotic checkpoint for cancer therapy with NMS-P715, a novel MPS1 kinase inhibitor
    Colombo, Riccardo
    Caldarelli, Marina
    Mennecozzi, Milena
    Giorgini, Maria L.
    Sola, Francesco
    Cappella, Paolo
    Ballinari, Dario
    Perrera, Claudia
    Depaolini, Stefania Re
    Rusconi, Luisa
    Avanzi, Nilla
    Volpi, Daniele
    Bossi, Roberto
    Bertrand, Jay A.
    Pesenti, Enrico
    Isacchi, Antonella
    Donati, Daniele
    Moll, Jurgen
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)