Biomarkers in Solid-Organ Transplantation

被引：10

作者：

Gieser, G. ^{[1
]}

Harigaya, H. ^{[1
]}

Colangelo, P. M. ^{[1
]}

Burckart, G. ^{[1
]}

机构：

[1] US FDA, Off Clin Pharmacol, Ctr Drug Evaluat, Silver Spring, MD USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2011年 / 90卷 / 02期

关键词：

INDEPENDENT PREDICTOR; CYCLOSPORINE; RECIPIENTS; IMMUNOSUPPRESSION; INJURY;

D O I：

10.1038/clpt.2011.75

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This workshop was organized by the US Food and Drug Administration (FDA) Office of Clinical Pharmacology Review Team supporting the Division of Special Pathogen and Transplant Products in the Center for Drug Evaluation and Research. The main goal of the workshop was to enhance the knowledge base regarding biomarkers in solid-organ transplantation via presentation and discussion of scientific findings.

引用

页码：217 / 220

页数：4

共 10 条

[1] Immune Phenotype Predicts Risk for Posttransplantation Squamous Cell Carcinoma [J].

Carroll, Robert P. ;

Segundo, David San ;

Hollowood, Kevin ;

Marafioti, Teresa ;

Clark, Taane G. ;

Harden, Paul N. ;

Wood, Kathryn J. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2010, 21 (04) :713-722

[2] Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimens [J].

Dantal, J ;

Hourmant, M ;

Cantarovich, D ;

Giral, M ;

Blancho, G ;

Dreno, B ;

Soulillou, JP .

LANCET, 1998, 351 (9103) :623-628

[3] Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose [J].

Klawitter, Jost ;

Haschke, Manuel ;

Kahle, Christine ;

Dingmann, Colleen ;

Klawitter, Jelena ;

Leibfritz, Dieter ;

Christians, Uwe .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 70 (02) :241-251

[4] Anti-Human Leukocyte Antigen and Donor-Specific Antibodies Detected by Luminex Posttransplant Serve as Biomarkers for Chronic Rejection of Renal Allografts [J].

Lachmann, Nils ;

Terasaki, Paul I. ;

Budde, Klemens ;

Liefeldt, Lutz ;

Kahl, Andreas ;

Reinke, Petra ;

Pratschke, Johann ;

Rudolph, Birgit ;

Schmidt, Danilo ;

Salama, Abdulgabar ;

Schoenemann, Constanze .

TRANSPLANTATION, 2009, 87 (10) :1505-1513

[5] Integrative Urinary Peptidomics in Renal Transplantation Identifies Biomarkers for Acute Rejection [J].

Ling, Xuefeng B. ;

Sigdel, Tara K. ;

Lau, Kenneth ;

Ying, Lihua ;

Lau, Irwin ;

Schilling, James ;

Sarwal, Minnie M. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2010, 21 (04) :646-653

[6]

Mishra Jaya, 2005, Lancet, V365, P1231, DOI 10.1016/S0140-6736(05)74811-X

[7] Pharmacodynamic monitoring of cyclosporine A in renal allograft recipients shows a quantitative relationship between immunosuppression and the occurrence of recurrent infections and malignancies [J].

Sommerer, Claudia ;

Konstandin, Mathias ;

Dengler, Thomas ;

Schmidt, Jan ;

Meuer, Stefan ;

Zeier, Martin ;

Giese, Thomas .

TRANSPLANTATION, 2006, 82 (10) :1280-1285

[8] Plasma Procalcitonin Is an Independent Predictor of Graft Failure Late After Renal Transplantation [J].

van Ree, Rutger M. ;

de Vries, Aiko P. J. ;

Oterdoom, Leendert H. ;

Seelen, Marc A. ;

Gansevoort, Ron T. ;

Schouten, Jan P. ;

Struck, Joachim ;

Navis, Gerjan ;

Gans, Reinold O. B. ;

van der Heide, Jaap J. Homan ;

van Son, Willem J. ;

Bakker, Stephan J. L. .

TRANSPLANTATION, 2009, 88 (02) :279-287

[9] Pharmacodynamic Monitoring of Calcineurin Inhibition Therapy: Principles, Performance, and Perspectives [J].

van Rossum, Huub H. ;

de Fijter, Johan W. ;

van Pelt, Johannes .

THERAPEUTIC DRUG MONITORING, 2010, 32 (01) :3-10

[10] High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients [J].

van Timmeren, Mirjan M. ;

Vaidya, Vishal S. ;

van Ree, Rutger M. ;

Oterdoom, Leendert H. ;

de Vries, Aiko P. J. ;

Gans, Reinold O. B. ;

van Goor, Harry ;

Stegeman, Coen A. ;

Bonventre, Joseph V. ;

Bakker, Stephan J. L. .

TRANSPLANTATION, 2007, 84 (12) :1625-1630

← 1 →