Regioselective ester cleavage during the preparation of bisphosphonate methacrylate monomers

被引：15

作者：

Chougrani, Kamel ^{[1
]}

Niel, Gilles ^{[1
]}

Boutevin, Bernard ^{[1
]}

David, Ghislain ^{[1
]}

机构：

[1] Ecole Natl Super Chim, Inst Charles Gerhardt, CNRS, UMR 5253, F-34296 Montpellier 5, France

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 7卷

关键词：

bifunctional monomer; phosphonic acid; regioselective ester cleavage; ACRYLIC PHOSPHONIC-ACIDS; RADICAL POLYMERIZATION; DENTAL ASPECTS; DERIVATIVES; POLYMERS; AGENTS;

D O I：

10.3762/bjoc.7.46

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New functional monomers bearing a methacrylate, a bisphosphonate function and, for most, an internal carboxylate group, were prepared for incorporation into copolymers with adhesive or anticorrosive properties. Methanolysis of some trimethylsilyl bisphosphonate esters not only deprotects the desired bisphosphonate function but also regioselectively cleaves the alkyl ester function without affecting the methacrylate ester.

引用

页码：364 / 368

页数：5

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