Microcantilever biosensors for chemicals and bioorganisms

被引:85
作者
Buchapudi, Koutilya R. [2 ]
Huang, Xin [1 ]
Yang, Xin [2 ]
Ji, Hai-Feng [1 ]
Thundat, Thomas [3 ]
机构
[1] Drexel Univ, Dept Chem, Philadelphia, PA 19104 USA
[2] Louisiana Tech Univ, Inst Micromfg, Ruston, LA 71272 USA
[3] Univ Alberta, Dept Chem & Mat Engn, Edmonton, AB T6G2V4, Canada
基金
中国国家自然科学基金; 美国国家卫生研究院;
关键词
BACILLUS-ANTHRACIS SPORES; ESCHERICHIA-COLI O157-H7; C-REACTIVE PROTEIN; LABEL-FREE; NANOMECHANICAL BIOSENSORS; COATED MICROCANTILEVER; ELECTRICAL DETECTION; CANTILEVER SENSOR; SURFACE STRESS; MICROFABRICATED CANTILEVER;
D O I
10.1039/c0an01007c
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In the last fifteen years, microcantilevers (MCLs) have been emerging as a sensitive tool for the detection of chemicals and bioorganisms. Because of their small size, lightweight, and high surface-to-volume ratio, MCL-based sensors improve our capability to detect and identify biological agents by orders of magnitude. A biosensor is a device for the detection of an analyte that combines a biological component with a physicochemical detector component. The MCL biosensors have recently been reviewed in several papers. All of these papers were organized based on the sensing biological elements (antibody, enzyme, proteins, etc.) for recognition of analytes. In this review, we intend to summarize the microcantilever biosensors in a format of each specific chemical and bioorganism species to make information on individual biosensors easily accessible. We did this to aid researchers to locate relevant references.
引用
收藏
页码:1539 / 1556
页数:18
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