Metal-assisted red light-induced efficient DNA cleavage by dipyridoquinoxaline-copper(II) complex

被引:81
作者
Dhar, S [1 ]
Senapati, D [1 ]
Reddy, PAN [1 ]
Das, PK [1 ]
Chakravarty, AR [1 ]
机构
[1] Indian Inst Sci, Dept Inorgan & Phys Chem, Bangalore 560012, Karnataka, India
关键词
D O I
10.1039/b308344f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Complete cleavage of double stranded pUC19 DNA by the complex [Cu(dpq)(2)(H2O)](ClO4)(2) (dpq, dipyridoquinoxaline) has been observed on irradiation at 694 nm from a pulsed ruby laser, assisted by the metal d-band transition as well as the quinoxaline triplet states in the absence of any external additives.
引用
收藏
页码:2452 / 2453
页数:2
相关论文
共 19 条
  • [1] Ackroyd R, 2001, PHOTOCHEM PHOTOBIOL, V74, P656, DOI 10.1562/0031-8655(2001)074<0656:THOPAP>2.0.CO
  • [2] 2
  • [3] BATLLE AMD, 1993, J PHOTOCH PHOTOBIO B, V20, P5
  • [4] Efficient copper (II)-mediated nuclease activity of ortho-quinacridines
    Baudoin, O
    Teulade-Fichou, MP
    Vigneron, JP
    Lehn, JM
    [J]. CHEMICAL COMMUNICATIONS, 1998, (21) : 2349 - 2350
  • [5] Photosensitized generation of hydroxyl radical by eight new sulfur and selenium analogs of psoralen
    Collet, M
    Hoebeke, M
    Piette, J
    Jakobs, A
    Lindqvist, L
    VandeVorst, A
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1996, 35 (03) : 221 - 231
  • [6] Photosensitized singlet oxygen and its applications
    DeRosa, MC
    Crutchley, RJ
    [J]. COORDINATION CHEMISTRY REVIEWS, 2002, 233 : 351 - 371
  • [7] Efficient visible light induced nuclease activity of a ternary mono-1,10-phenanthroline copper(II) complex containing 2-(methylthio)ethylsalicylaidimine
    Dhar, S
    Chakravarty, AR
    [J]. INORGANIC CHEMISTRY, 2003, 42 (08) : 2483 - 2485
  • [8] Transition metal Kinamycin model as a DNA photocleaver for hypoxic environments: bis(9-diazo-4,5-diazafluorene)copper(II) nitrate
    Eppley, HJ
    Sato, SM
    Ellington, AD
    Zaleski, JM
    [J]. CHEMICAL COMMUNICATIONS, 1999, (23) : 2405 - 2406
  • [9] FIEL RJ, 1981, CANCER RES, V41, P3543
  • [10] Henderson BW, 2000, CANCER RES, V60, P525