Factors contributing to the duration of untreated prodromal positive symptoms in individuals at ultra-high risk for psychosis

被引：12

作者：

Chon, Myong-Wuk ^{[1
,2
]}

Lee, Tae Young ^{[3
]}

Kim, Sung Nyun ^{[1
]}

Huh, Min Jung ^{[1
,2
]}

Park, Hye Youn ^{[2
]}

Lee, Cho Rong ^{[4
]}

Shin, Na Young ^{[4
]}

Kwon, Jun Soo ^{[1
,2
,3
,4
]}

机构：

[1] Seoul Natl Univ Hosp, Dept Neuropsychiat, Seoul 110744, South Korea

[2] Seoul Natl Univ Coll Med, Dept Psychiat, Seoul 110744, South Korea

[3] SNU MRC, Inst Human Behav Med, Seoul, South Korea

[4] Seoul Natl Univ Coll Nat Sci, Dept Brain & Cognit Sci, Seoul 110744, South Korea

来源：

SCHIZOPHRENIA RESEARCH | 2015年 / 162卷 / 1-3期

关键词：

Ultra-high risk for psychosis; Psychosis; Duration of untreated prodromal positive symptoms; Functional decline; Delayed care; CLINICAL HIGH-RISK; SCHIZOPHRENIA; METAANALYSIS; RELIABILITY; INTERVIEW; DEFICITS; VALIDITY; SCALE;

D O I：

10.1016/j.schres.2015.01.013

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Individuals at ultra-high risk (UHR) for psychosis experience a considerable delay before appropriate clinical attention is provided. Therefore, we investigated the correlates of this delay by examining clinical, sociodemographic and neuropsychological contributors to the duration of untreated prodromal positive symptoms (DUPP) in them (n = 73). The slowly progressive mode of functional decline, defined as a small percentage drop in the Global Assessment of Functioning (GAF) score within the past year, and male gender, explained a considerable portion of the DUPP in the multivariate regression model (F = 9.269, p < 0.001). Slower functional decline may be correlated with delayed care during the UHR period. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：64 / 66

页数：3

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