Solving the FYVE domain-PtdIns(3)P puzzle

被引：13
|
作者：
Driscoll, PC
机构：
[1] UCL, Dept Biochem & Mol Biol, London WC1E 6BT, England
[2] Ludwig Inst Canc Res, London W1W 7BS, England
来源：
NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 04期
关键词：
D O I：
10.1038/86144
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent crystallographic analyses of membrane-tethering FYVE finger domains from proteins involved in the regulation of endocytic vesicle trafficking have led to conflicting views of the precise nature of the contacts formed with the specific phospholipid ligand. New NMR data obtained for ligand-bound forms of a FYVE domain help resolve the atomic details of this interaction.
引用
收藏
页码：287 / 290
页数：4
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