Solving the FYVE domain-PtdIns(3)P puzzle

被引:13
|
作者
Driscoll, PC
机构
[1] UCL, Dept Biochem & Mol Biol, London WC1E 6BT, England
[2] Ludwig Inst Canc Res, London W1W 7BS, England
关键词
D O I
10.1038/86144
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent crystallographic analyses of membrane-tethering FYVE finger domains from proteins involved in the regulation of endocytic vesicle trafficking have led to conflicting views of the precise nature of the contacts formed with the specific phospholipid ligand. New NMR data obtained for ligand-bound forms of a FYVE domain help resolve the atomic details of this interaction.
引用
收藏
页码:287 / 290
页数:4
相关论文
共 50 条
  • [1] Solving the FYVE domain–PtdIns(3)P puzzle
    Paul C. Driscoll
    Nature Structural Biology, 2001, 8 : 287 - 290
  • [2] FYVE fingers bind Ptdins(3)P
    Gaullier, JM
    Simonsen, A
    D'Arrigo, A
    Bremnes, B
    Stenmark, H
    Aasland, R
    NATURE, 1998, 394 (6692) : 432 - 433
  • [3] FYVE fingers bind PtdIns(3)P
    Jean-Michel Gaullier
    Anne Simonsen
    Antonello D'Arrigo
    Bjørn Bremnes
    Harald Stenmark
    Rein Aasland
    Nature, 1998, 394 : 432 - 433
  • [4] Fluorescent FYVE Chimeras to Quantify PtdIns3P Synthesis During Autophagy
    Yakhine-Diop, S. M. S.
    Martinez-Chacon, G.
    Gonzalez-Polo, R. A.
    Fuentes, J. M.
    Niso-Santano, M.
    MOLECULAR CHARACTERIZATION OF AUTOPHAGIC RESPONSES, PT A, 2017, 587 : 257 - 269
  • [5] Regulating the activity of Akt by inhibiting the pleckstrin homology domain-PtdIns(3,4,5)P3 interaction using flavonoids
    Kang, Yerin
    Lee, Woonwoo
    Yoon, Youngdae
    FASEB JOURNAL, 2018, 32 (01):
  • [6] Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns (3,4,5)P3 interactions
    Luo, HBR
    Huang, YE
    Chen, JMC
    Saiardi, A
    Iijima, M
    Ye, KQ
    Huang, YF
    Nagata, E
    Devreotes, P
    Snyder, SH
    CELL, 2003, 114 (05) : 559 - 572
  • [7] PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    Antonia P. Sagona
    Ioannis P. Nezis
    Nina Marie Pedersen
    Knut Liestøl
    John Poulton
    Tor Erik Rusten
    Rolf I. Skotheim
    Camilla Raiborg
    Harald Stenmark
    Nature Cell Biology, 2010, 12 : 362 - 371
  • [8] FYVE zinc-finger proteins in the plant model Arabidopsis thaliana:: identification of PtdIns3P-binding residues by comparison of classic and variant FYVE domains
    Jensen, RB
    La Cour, T
    Albrethsen, J
    Nielsen, M
    Skriver, K
    BIOCHEMICAL JOURNAL, 2001, 359 : 165 - 173
  • [9] PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    Sagona, Antonia P.
    Nezis, Ioannis P.
    Pedersen, Nina Marie
    Liestol, Knut
    Poulton, John
    Rusten, Tor Erik
    Skotheim, Rolf I.
    Raiborg, Camilla
    Stenmark, Harald
    NATURE CELL BIOLOGY, 2010, 12 (04) : 362 - U140
  • [10] Phosphatidylinositol 3-phosphate recognition by the FYVE domain
    Kutateladze, TG
    Ogburn, KD
    Watson, WT
    de Beer, T
    Emr, SD
    Burd, CG
    Overduin, M
    MOLECULAR CELL, 1999, 3 (06) : 805 - 811