Novel 5-alkyl(aryl)-substituted ribavirine analogues: synthesis and antiviral evaluation

被引:16
作者
Chudinov, Mikhail V. [1 ]
Matveev, Andrey V. [1 ]
Prutkov, Alexander N. [1 ]
Konstantinova, Irina D. [2 ]
Fateev, Ilja V. [2 ]
Prasolov, Vladimir S. [3 ]
Smirnova, Olga A. [3 ]
Ivanov, Alexander V. [3 ]
Galegov, Georgy A. [4 ]
Deryabin, Petr G. [4 ]
机构
[1] Moscow Technol Univ, MV Lomonosov Fine Chem Technol Inst, Moscow 117571, Russia
[2] Russian Acad Sci, MM Shemyakin Yu A Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
[3] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 119991, Russia
[4] DI Ivanovsky Res Inst Virol, Moscow 123098, Russia
基金
俄罗斯基础研究基金会;
关键词
RESISTANT PANCREATIC-CANCER; ANTICANCER ACTIVITY;
D O I
10.1016/j.mencom.2016.04.012
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Novel 5-alkyl(aryl)-substituted 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamides were prepared in three steps. Their antiviral activity was evaluated.
引用
收藏
页码:214 / 216
页数:3
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