1,3-Disulfonic acid imidazolium hydrogen sulfate: a reusable and efficient ionic liquid for the one-pot multi-component synthesis of pyrimido[4,5-b]-quinoline derivatives

被引：38
作者：
Mohammadi, Kamal [1 ]
Shirini, Farhad [1 ]
Yahyazadeh, Asieh [1 ]
机构：
[1] Univ Guilan, Coll Sci, Dept Chem, Rasht, Iran
来源：
RSC ADVANCES | 2015年 / 5卷 / 30期
基金：
美国国家科学基金会;
关键词：
CATALYST; 3-COMPONENT; ANTIOXIDANT; PROTECTION; DESIGN;
D O I：
10.1039/c5ra02198g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A green, simple and convenient method for the synthesis of pyrimido-[4,5-b]quinoline derivatives has been developed through a three-component one-pot condensation of 6-amino-1,3-dimethyluracil, aldehydes, and cyclic 1,3-diketones in the presence of 1,3-disulfonic acid imidazolium hydrogen sulfate [dsim]HSO4 as an efficient catalyst. The present methodology offers several advantages such as excellent yields, simple procedure, short reaction times, high yields of the products and easy work-up procedures. Also, the catalyst was readily recovered and could be reused several times without a noticeably decrease in its activity.
引用
收藏
页码：23586 / 23590
页数：5
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