DETECTION METHOD OF TOXOPLASMA GONDII TACHYZOITES

被引：0

作者：

Eassa, Souzan ^{[1
]}

Bose, Chhanda ^{[2
]}

Alusta, Pierre ^{[2
,3
]}

Tarasenko, Olga ^{[1
]}

机构：

[1] Univ Arkansas, Little Rock, AR 72204 USA

[2] Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72204 USA

[3] Natl Ctr Toxicol Res, FDA Labs, Jefferson, AR USA

来源：

BIOLOGY, NANOTECHNOLOGY, TOXICOLOGY, AND APPLICATIONS: PROCEEDINGS OF THE 5TH BIONANOTOX AND APPLICATIONS INTERNATIONAL RESEARCH CONFERENCE | 2011年 / 1326卷

关键词：

RISK-FACTORS; INFECTION; OLIGOSACCHARIDES; GLYCOSYLATION; RECOGNITION; PREGNANCY; ROLES;

D O I：

10.1063/1.3587472

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Tachyzoites are considered to be the most important stage of Toxoplasma gondii which causes toxoplasmosis. T. gondii is, an obligate intracellular parasite which infects a wide range of cells. The present study was designed to develop a method for an early detection of T. gondii tachyzoites. The method comprised of a binding assay which was analyzed using principal component and cluster analysis. Our data showed that glycoconjugates GC1, GC2, GC3 and GC10 exhibit a significantly higher binding affinity for T. gondii tachyzoites as compared to controls (T. gondii only, PAA only, GC 1, 2, 3, and 10 only).

引用

页码：157 / 164

页数：8

共 24 条

[1] Toxoplasma dye test using cell culture derived tachyzoites [J].