Optical Resonator Biosensors: Molecular Diagnostic and Nanoparticle Detection on an Integrated Platform

被引:99
作者
Baaske, Martin [1 ]
Vollmer, Frank [1 ]
机构
[1] Max Planck Inst Sci Light, Lab Biophoton & Biosensing, D-91058 Erlangen, Germany
关键词
label-free biosensing; lab-on-a-chip; microfluidic integration; nanoparticle detection; optical resonator; WHISPERING-GALLERY MODES; LABEL-FREE DETECTION; MICRORING-RESONATOR; SINGLE MOLECULES; SHIFT; MANIPULATION; LITHOGRAPHY; FABRICATION; SENSORS;
D O I
10.1002/cphc.201100757
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Optical resonator biosensors are emerging as one of the most sensitive microsystem biodetection technology that does not require amplification or labeling of the analyte. This minireview provides a scholarly introduction to this research area and reviews current advances in molecular diagnostics and nanoparticle detection.
引用
收藏
页码:427 / 436
页数:10
相关论文
共 69 条
[31]   Whispering-gallery-mode resonators as frequency references. I. Fundamental limitations [J].
Matsko, Andrey B. ;
Savchenkov, Anatoby A. ;
Yu, Nan ;
Maleki, Lute .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, 2007, 24 (06) :1324-1335
[32]   Nanolayer characterization through wavelength multiplexing of a microsphere resonator [J].
Noto, M ;
Vollmer, F ;
Keng, D ;
Teraoka, I ;
Arnold, S .
OPTICS LETTERS, 2005, 30 (05) :510-512
[33]   Detection of protein orientation on the silica microsphere surface using transverse electric/transverse magnetic whispering gallery modes [J].
Noto, Mayumi ;
Keng, David ;
Teraoka, Iwao ;
Arnold, Stephen .
BIOPHYSICAL JOURNAL, 2007, 92 (12) :4466-4472
[34]   Higher-order optical resonance node detection of integrated disk microresonator [J].
Ostrowski, M. ;
Pignalosa, P. ;
Smith, H. ;
Yi, Y. .
OPTICS LETTERS, 2011, 36 (16) :3042-3044
[35]   Soft lithography replica molding of critically coupled polymer microring resonators [J].
Poon, JKS ;
Huang, YY ;
Paloczi, GT ;
Yariv, A .
IEEE PHOTONICS TECHNOLOGY LETTERS, 2004, 16 (11) :2496-2498
[36]   High-Q microsphere biosensor - analysis for adsorption of rodlike bacteria [J].
Ren, Hai-Cang ;
Vollmer, Frank ;
Arnold, Stephen ;
Libchaber, Albert .
OPTICS EXPRESS, 2007, 15 (25) :17410-17423
[37]   Optical forces due to spherical microresonators and their manifestation in optically induced orbital motion of nanoparticles [J].
Rubin, J. T. ;
Deych, L. I. .
PHYSICAL REVIEW A, 2011, 84 (02)
[38]   Nanoparticle-based protein detection by optical shift of a resonant microcavity [J].
Santiago-Cordoba, Miguel A. ;
Boriskina, Svetlana V. ;
Vollmer, Frank ;
Demirel, Melik C. .
APPLIED PHYSICS LETTERS, 2011, 99 (07)
[39]   The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements [J].
Shi, Leming ;
Reid, Laura H. ;
Jones, Wendell D. ;
Shippy, Richard ;
Warrington, Janet A. ;
Baker, Shawn C. ;
Collins, Patrick J. ;
de Longueville, Francoise ;
Kawasaki, Ernest S. ;
Lee, Kathleen Y. ;
Luo, Yuling ;
Sun, Yongming Andrew ;
Willey, James C. ;
Setterquist, Robert A. ;
Fischer, Gavin M. ;
Tong, Weida ;
Dragan, Yvonne P. ;
Dix, David J. ;
Frueh, Felix W. ;
Goodsaid, Federico M. ;
Herman, Damir ;
Jensen, Roderick V. ;
Johnson, Charles D. ;
Lobenhofer, Edward K. ;
Puri, Raj K. ;
Scherf, Uwe ;
Thierry-Mieg, Jean ;
Wang, Charles ;
Wilson, Mike ;
Wolber, Paul K. ;
Zhang, Lu ;
Amur, Shashi ;
Bao, Wenjun ;
Barbacioru, Catalin C. ;
Lucas, Anne Bergstrom ;
Bertholet, Vincent ;
Boysen, Cecilie ;
Bromley, Bud ;
Brown, Donna ;
Brunner, Alan ;
Canales, Roger ;
Cao, Xiaoxi Megan ;
Cebula, Thomas A. ;
Chen, James J. ;
Cheng, Jing ;
Chu, Tzu-Ming ;
Chudin, Eugene ;
Corson, John ;
Corton, J. Christopher ;
Croner, Lisa J. .
NATURE BIOTECHNOLOGY, 2006, 24 (09) :1151-1161
[40]   Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection [J].
Shopova, S. I. ;
Rajmangal, R. ;
Holler, S. ;
Arnold, S. .
APPLIED PHYSICS LETTERS, 2011, 98 (24)