Applications of acellular human amniotic membrane in regenerative medicine

被引:15
|
作者
Doudi, Shaghayegh [1 ]
Barzegar, Mansoureh [2 ,3 ]
Taghavi, Elham Angouraj [1 ]
Eini, Mohammad [4 ]
Ehterami, Arian [5 ]
Stokes, Karen [3 ]
Alexander, Jonathan S. [3 ]
Salehi, Majid [6 ,7 ,8 ]
机构
[1] Shahroud Univ Med Sci, Student Res Comm, Sch Med, Shahroud, Iran
[2] Johns Hopkins Sch Med, Wilmer Eye Inst, Dept Ophthalmol, Baltimore, MD USA
[3] Louisiana State Univ Hlth Sci Ctr Shreveport, Dept Mol & Cellular Physiol, Shreveport, LA USA
[4] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Tissue Engn & Appl Cell Sci, Tehran, Iran
[5] Univ Zurich, Inst Regenerat Med IREM, Zurich, Switzerland
[6] Shahroud Univ Med Sci, Sch Med, Dept Tissue Engn, Shahroud, Iran
[7] Shahroud Univ Med Sci, Tissue Engn & Stem Cells Res Ctr, Shahroud, Iran
[8] Shahroud Univ Med Sci, Sexual Hlth & Fertil Res Ctr, Shahroud, Iran
关键词
Acellular; Amniotic membrane; Regenerative medicine; DELIVERY-SYSTEM; SCAFFOLD; MATRIX; MODEL; DECELLULARIZATION; TRANSPLANTATION; CULTURE; REPAIR; CELLS;
D O I
10.1016/j.lfs.2022.121032
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The human amniotic membrane (hAM) surrounds and protects the fetus. It mainly consists of a thick basement membrane and an avascular stromal matrix. The structural, physical, and biological properties of AM make it a wonderful choice to use in regenerative medicine applications. This review discusses recent applications of hAM in skin transplantation and wound healing, ophthalmology, orthopedics, cell culture matrix, cell delivery system, cardiac injury, male and female reproductive systems, and liver. Moreover, an overview is presented on the advantages and disadvantages of using hAM and some methods to systematically refine and standardize hAM preparation.
引用
收藏
页数:11
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