A case report and literature review of chronic graft-versus-host disease manifesting as polymyositis

被引：6
|
作者：
Michelis, Fotios V. [1 ]
Bril, Vera [2 ]
Lipton, Jeffrey H. [1 ]
机构：
[1] Univ Toronto, Univ Hlth Network, Princess Margaret Canc Ctr, Allogene Blood & Marrow Transplant Program, Toronto, ON M5G2M9, Canada
[2] Univ Toronto, Univ Hlth Network, Dept Med, Div Neurol, Toronto, ON M5G2M9, Canada
来源：
INTERNATIONAL JOURNAL OF HEMATOLOGY | 2015年 / 102卷 / 01期
关键词：
Polymyositis; Allogeneic hematopoietic cell transplantation; Chronic graft-versus-host disease; Hydroxychloroquine; DONOR LYMPHOCYTE INFUSION; CHRONIC GVHD; DERMATOMYOSITIS; CRITERIA;
D O I：
10.1007/s12185-015-1768-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Polymyositis (PM) is a rare but documented manifestation of chronic graft-versus-host disease (cGvHD) post allogeneic hematopoietic cell transplantation (HCT). We present the case of a 70-year-old male patient who developed severe cGvHD-related PM 3 years after undergoing allogeneic HCT for acute myeloid leukemia. The patient responded to steroids and was maintained long-term with hydroxychloroquine as a steroid-sparing agent. We review the literature concerning the diagnosis and treatment of PM as cGvHD as well as the differentiation of this manifestation from other forms of PM.
引用
收藏
页码：144 / 146
页数：3
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