Correlative multiscale tomography of biological materials

被引:16
作者
Bradley, Robert S. [1 ]
Withers, Philip J. [2 ]
机构
[1] Univ Manchester, Manchester M13 9PL, Lancs, England
[2] Univ Manchester, Sch Mat, Manchester M13 9PL, Lancs, England
基金
英国工程与自然科学研究理事会;
关键词
RAY COMPUTED-TOMOGRAPHY; GOLD NANOPARTICLES; CONTRAST AGENTS; MICROSCOPY; FLUORESCENCE; DISTRIBUTIONS; CHROMOSOMES; FATIGUE;
D O I
10.1557/mrs.2016.137
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The intricate hierarchical microstructures typical of biological materials give rise to fascinating combinations of anisotropic mechanical properties that can surpass those of man-made materials. The linking together of three-dimensional (3D) imaging techniques has the potential to reveal these structures in unprecedented detail. However, a complete understanding can only be reached if the relationship between structure and mechanical properties can be elucidated. X-ray-computed tomography (CT) is uniquely placed to image such structures across a wide range of length scales. We review recent technical advances that are leading to improved contrast and spatial resolution. We highlight how time-lapse CT 3D studies can track the response of hierarchical microstructures to mechanical loading.
引用
收藏
页码:549 / 554
页数:6
相关论文
共 68 条
[1]   Application of Micro-Computed Tomography With Iodine Staining to Cardiac Imaging, Segmentation, and Computational Model Development [J].
Aslanidi, Oleg V. ;
Nikolaidou, Theodora ;
Zhao, Jichao ;
Smaill, Bruce H. ;
Gilbert, Stephen H. ;
Holden, Arun V. ;
Lowe, Tristan ;
Withers, Philip J. ;
Stephenson, Robert S. ;
Jarvis, Jonathan C. ;
Hancox, Jules C. ;
Boyett, Mark R. ;
Zhang, Henggui .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2013, 32 (01) :8-17
[2]   Extreme strength observed in limpet teeth [J].
Barber, Asa H. ;
Lu, Dun ;
Pugno, Nicola M. .
JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2015, 12 (105)
[3]   Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone [J].
Barth, Holly D. ;
Zimmermann, Elizabeth A. ;
Schaible, Eric ;
Tang, Simon Y. ;
Alliston, Tamara ;
Ritchie, Robert O. .
BIOMATERIALS, 2011, 32 (34) :8892-8904
[4]   Architectured materials in engineering and biology: fabrication, structure, mechanics and performance [J].
Barthelat, F. .
INTERNATIONAL MATERIALS REVIEWS, 2015, 60 (08) :413-430
[5]   Coherent X-Ray Imaging of Collagen Fibril Distributions within Intact Tendons [J].
Berenguer, Felisa ;
Bean, Richard J. ;
Bozec, Laurent ;
Vila-Comamala, Joan ;
Zhang, Fucai ;
Kewish, Cameron M. ;
Bunk, Oliver ;
Rodenburg, John M. ;
Robinson, Ian K. .
BIOPHYSICAL JOURNAL, 2014, 106 (02) :459-466
[6]   Laboratory soft-x-ray microscope for cryotomography of biological specimens [J].
Bertilson, Michael ;
von Hofsten, Olov ;
Vogt, Ulrich ;
Holmberg, Anders ;
Christakou, Athanasia E. ;
Hertz, Hans M. .
OPTICS LETTERS, 2011, 36 (14) :2728-2730
[7]   Rapid, automated imaging of mouse articular cartilage by microCT for early detection of osteoarthritis and finite element modelling of joint mechanics [J].
Borges, P. Das Neves ;
Forte, A. E. ;
Vincent, T. L. ;
Dini, D. ;
Marenzana, M. .
OSTEOARTHRITIS AND CARTILAGE, 2014, 22 (10) :1419-1428
[8]   X-ray phase-contrast imaging: from pre-clinical applications towards clinics [J].
Bravin, Alberto ;
Coan, Paola ;
Suortti, Pekka .
PHYSICS IN MEDICINE AND BIOLOGY, 2013, 58 (01) :R1-R35
[9]   Correlative Tomography [J].
Burnett, T. L. ;
McDonald, S. A. ;
Gholinia, A. ;
Geurts, R. ;
Janus, M. ;
Slater, T. ;
Haigh, S. J. ;
Ornek, C. ;
Almuaili, F. ;
Engelberg, D. L. ;
Thompson, G. E. ;
Withers, P. J. .
SCIENTIFIC REPORTS, 2014, 4
[10]   Optimal Iodine Staining of Cardiac Tissue for X-Ray Computed Tomography [J].
Butters, Timothy D. ;
Castro, Simon J. ;
Lowe, Tristan ;
Zhang, Yanmin ;
Lei, Ming ;
Withers, Philip J. ;
Zhang, Henggui .
PLOS ONE, 2014, 9 (08)