Cowpox infection transmitted from a domestic cat

被引：19

作者：

Bonnekoh, Bernd ^{[1
]}

Falk, Kristof ^{[1
]}

Reckling, Karl-Friedrich

Kenklies, Susanne

Nitsche, Andreas ^{[2
]}

Ghebremedhin, Beniam ^{[3
]}

Pokrywka, Anna ^{[1
]}

Franke, Ingolf ^{[1
]}

Thriene, Bernd ^{[4
]}

Koenig, Wolfgang ^{[3
]}

Pauli, Georg ^{[2
]}

Gollnick, Harald ^{[1
]}

机构：

[1] Univ Magdeburg, Klin & Poliklin Dermatol & Venerol, D-39120 Magdeburg, Germany

[2] Robert Koch Inst, Konsiliar Pockenviren, D-1000 Berlin, Germany

[3] Univ Magdeburg, Inst Med Mikrobiol, D-39120 Magdeburg, Germany

[4] Univ Klinikum Magdeburg AoR, Krakenhaushyg, Arzt Direktorat, Magdeburg, Germany

来源：

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT | 2008年 / 6卷 / 03期

关键词：

cowpox; variola vera; vaccinia immunization; cidofovir; zoonoses; occupational skin disease;

D O I：

10.1111/j.1610-0387.2007.06546.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A 21-year-old immunocompetent woman developed a cowpox infection, while working as a veterinarian's assistant in a rural area. She had never received vaccinia immunization and came in contact with a fatally-infected house cat. Under symptomatic treatment, the infection remained localized to one cheek and cleared over 3 weeks with substantial dermal-subcutaneous tissue destruction. Orthopoxvirus detection by PCR is a modern diagnostic standard, in addition to identification by negative-contrast electron microscopy. A promising therapeutic option is ciclofovir, but this virostatic drug is not yet approved for the treatment of cowpox.

引用

页码：210 / 213

页数：4

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